Marist College, B.A., 1970, Biology, Poughkeepsie, NY
North Carolina State University, M.S., 1971, Microbiology/Marine Science, Raleigh, NC
North Carolina State University, Ph.D., 1975, Microbiology/Marine Science, Raleigh, NC

Experience:

• 1975-1979, Research Associate/Visiting Assistant Professor, University of Texas, Marine Science Institute, Port Aransas, Texas (Summer Session)
• 1975-1980, Postdoctoral Research Associate, University of Texas, Austin, Texas
• 1980-1984, Supervisory Microbiology, Division of Microbiology, National Center for Toxicological
• Research, Jefferson, AR
• 1984-1988, Chief, Research Branch, Division of Microbiology, National Center for Toxicological Research, Jefferson, AR
• 1988-present, Director, Division of Microbiology, National Center for Toxicological Research, Jefferson, AR.

Honors:

• FDA Science Award, 2000
• Appointment, Senior Biomedical Research Service Scientist, 1995.
• Deputy Associate Director for Research, Office of Research, NCTR, 1991-1994.
• Elected, ASM Foundation for Microbiology Lecturer, 1994-1996.
• Elected, Chairman for the American Society for Microbiology – Applied & Environmental Microbiology Division, 1994-1996.
• Received Public Health Service Equal Opportunity Achievement Award, 1993.
• Recognition of Research Accomplishment, journal cover, Applied and Environmental Microbiology.
• Chairman, Gordon Research Conference on Applied and Environmental Microbiology, 1991, 1993, 1995.
• FDA Award of Merit, 1989.
• Appointed as an expert member of the World Health Organization, 1992-present.
• Serves on Science Advisory Board for Rutgers University, University of North Carolina, and California Polytechnic State University.
• Elected Chairman for the American Society for Microbiology, Applied and Environmental Microbiology Division, 1994 - 1996.
• Group Award, FDA for effort in the FDA Research Integration Plan, 1992.
• FDA Award for Commendable Service, 1986.

Current Primary Research Interests:

• The determination of the role of intestinal microflora in the activation or detoxification of xenobiotics
• The use of microorganisms as models to predict the metabolic pathways that drugs are metabolized in mammals
• The role that microorganisms have in the degradation and detoxification of potentially hazardous compounds
• Foodborne pathogen and methods development

Most Recent Publications (from a total of 252 publications).

• Assaf, N.A., Pothuluri, J.V., Wang, R.-F., Moffitt, C., and Cerniglia, C.E. "Bioassay procedure for the evaluation of erythromycin activity in aquaculture environments." J. World Aquaculture Soc., 30: 137-146 (1999).
  
  

• Castlebury, L.A., Sutherland, J.B., Tanner, L.A., Henderson, A.L., and Cerniglia, C.E. "Use of a bioassay to evaluate the toxicity of beauvericin to bacteria." World J. Microbiol. Biotechnol., 15: 119-121 (1999).
  
  

• Cerniglia, C.E. and S. Kotarski. 1999. Evaluation of veterinary drug residues in food for their potential to affect human intestinal microflora. J. Regulatory Toxicol. Pharmacol. 29: 238-261 (1999).
  
  

• Duhart, B.T., Jr., Zhang, D., Deck, J., Freeman, J.P., and Cerniglia, C.E. "Biotransformation of protriptyline by filamentous fungi and yeasts." Xenobiotica, 29: 733-746 (1999).
  
  

• Khan, A.A., Nawaz, M.S., Khan, S.A., and Cerniglia, C.E. "Identification of Aeromonas trota (hybridization group 13) by amplification of the aerolysin gene using polymerase chain reaction." Mol. Cell. Probes, 13: 93-98 (1999).
  
  

• Khan, S.A., Nawaz, M.S., Khan, A.A., and Cerniglia, C.E. "Direct in-gel hybridization of digoxigenin-labeled non-radioactive probes." Mol. Cell. Probes, 13: 233-237 (1999).
  
  

• Khan, S.A., Nawaz, M.S., Khan, A.A., and Cerniglia, C.E. "Simultaneous detection of erythromycin-resistant methylase genes ermA and ermC from Staphylococcus spp. by multiplex-PCR. J. Clin. Microbiol. 13: 381-387 (1999).
  
  

• Moody, J.D., Freeman, J.P., and Cerniglia, C.E. "Biotransformation of doxepin by Cunninghamella elegans." Drug Metab. Dispos. 27: 1157-1164 (1999).
  
  

• Nawaz, M.S., Khan, A.A., Khan, S.A., Paine, D.D., Pothuluri, J.V., and Cerniglia, C.E. "Biochemical and molecular characterization of erythromycin-resistant avian Staphylococcus spp. isolated from chickens." Poultry Sci., 78: 1191-1197 (1999).
  
  

• Pothuluri, J.V., Freeman, J.P., Fu, P.P., and Cerniglia, C.E. "Biotransformation of 1-nitrobenzo[e]pyrene by the fungus Cunninghamella elegans." J. Ind. Microbiol. Biotechnol. 22: 52-57 (1999).
  
  

• Rafii, F., Lunsford, P., Hehman, G., and Cerniglia, C.E. "Detection and purification of a catalase-peroxidase from Mycobacterium sp. Pyr-1." FEMS Microbiol. Lett. 173: 285-290 (1999).
  
  

• Wang, R.-F., Campbell, W.L., Cao, W.-W., Colvert, R.M., Holland, M.A., and Cerniglia, C.E. "Diagnosis of mouse hepatitis virus contamination in mouse population by using nude mice and RT-PCR." Mol. Cell. Probes, 13: 29-33 (1999).
  
  

• Khan, A.A., Nawaz, M.S., Khan, S.A., and Cerniglia, C.E. "Detection of multidrug-resistant Salmonella typhimurium DT104: A virulent pathogen by multiplex polymerase chain reaction," FEMS Microbiol. Lett., 182: 355-360 (2000).
  
  

• Khan, S.A., Nawaz, M.S., Khan, A.A., and Cerniglia, C.E. "Transfer of erythromycin resistance from poultry to human clinical strains of Staphylococcus aureus," J. Clin. Microbiol., 38: 1832-1838 (2000).
  
  

• Khan, S.A., Nawaz, M.S., Khan, A.A., Steele, R.S., and Cerniglia, C.E. "Characterization of erythromycin-resistant methylase genes from multiple drug resistant Staphylococcus spp. isolated from the milk of lactating cattle." Am. J. Vet. Res., (2000), (In press).
  
  

• Moody, J.D., Heinze, T.M., Hansen, E.B., Jr. and Cerniglia, C.E. Metabolism of the ethanolamine-type antihistamine diphenhydramine (Benadryl) by the fungus Cunninghamella elegans. Appl. Microbiol. Biotechnol. 53:310-315 (2000).
  
  

• Moody, J.D., Zhang, D., Heinze, T.M., and Cerniglia, C.E. "Transformation of amoxapine by Cunninghamella elegans." Appl. Environ. Microbiol. (2000), (In press).
  
  

• Shuttleworth, K.L., Sung, J., Kim, E., and Cerniglia, C.E. "Physiological and genetic comparisons of two aromatic hydrocarbon-degrading Sphingomonas strains." Mol. Cells, 10: 199-205 (2000).
  
  

• Wang, R.-F., Cao, W.-W., Khan, A.A. and Cerniglia, C.E. 2000. Cloning, Sequencing, and Expression in Escherichia coli of a Cytochrome P450 Gene from Cunninghamella elegans. FEMS Microbiol. Lett. (2000), (In press).
  
  

• Wang, R.-F., Khan, A.A., Cao, W.-W., and Cerniglia, C.E. "Cloning, sequencing and expression of the gene encoding enolase from Cunninghamella elegans." Mycol. Res. 104: 175-179 (2000).
  
  

• Wang, R.-F., Myers, M.J., Campbell, W.L., Cao, W.-W., Paine, D.D., and Cerniglia, C.E. "A rapid method for PCR detection of bovine materials in animal feedstuffs." J. Food Protect., 14: 1-5 (2000).