For Consumers
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Antiretroviral drugs used in the treatment of HIV infection
Drugs Used in the Treatment of HIV Infection
Click on drug brand name for additional information.
Multi-class Combination Products
| Brand Name | Generic Name | Manufacturer Name* | Approval Date | Time to Approval |
|---|---|---|---|---|
| Atripla | efavirenz, emtricitabine and tenofovir disoproxil fumarate | Bristol-Myers Squibb and Gilead Sciences | 12-July-06 | 2.5 months |
| Complera | emtricitabine, rilpivirine, and tenofovir disoproxil fumarate | Gilead Sciences | 10-August-11 | 6 months |
| Stribild | elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate | Gilead Sciences | 27-August-12 | 6 months |
Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
| Brand Name | Generic Name | Manufacturer Name* | Approval Date | Time to Approval |
|---|---|---|---|---|
| Combivir | lamivudine and zidovudine | GlaxoSmithKline | 27-Sep-97 | 3.9 months |
| Emtriva | emtricitabine, FTC | Gilead Sciences | 02-Jul-03 | 10 months |
| Epivir | lamivudine, 3TC | GlaxoSmithKline | 17-Nov-95 | 4.4 months |
| Epzicom | abacavir and lamivudine | GlaxoSmithKline | 02-Aug-04 | 10 months |
| Hivid | zalcitabine, dideoxycytidine, ddC (no longer marketed) | Hoffmann-La Roche | 19-Jun-92 | 7.6 months |
| Retrovir | zidovudine, azidothymidine, AZT, ZDV | GlaxoSmithKline | 19-Mar-87 | 3.5 months |
| Trizivir | abacavir, zidovudine, and lamivudine | GlaxoSmithKline | 14-Nov-00 | 10.9 months |
| Truvada | tenofovir disoproxil fumarate and emtricitabine | Gilead Sciences, Inc. | 02-Aug-04 | 5 months |
| Videx EC | enteric coated didanosine, ddI EC | Bristol Myers-Squibb | 31-Oct-00 | 9 months |
| Videx | didanosine, dideoxyinosine, ddI | Bristol Myers-Squibb | 9-Oct-91 | 6 months |
| Viread | tenofovir disoproxil fumarate, TDF | Gilead | 26-Oct-01 | 5.9 months |
| Zerit | stavudine, d4T | Bristol Myers-Squibb | 24-Jun-94 | 5.9 months |
| Ziagen | abacavir sulfate, ABC | GlaxoSmithKline | 17-Dec-98 | 5.8 months |
Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)
| Brand Name | Generic Name | Manufacturer Name* | Approval Date | Time to Approval |
|---|---|---|---|---|
| Edurant | rilpivirine | Tibotec Therapeutics | 20-May-11 | 10 months |
| Intelence | etravirine | Tibotec Therapeutics | 18-Jan-08 | 6 months |
| Rescriptor | delavirdine, DLV | Pfizer | 4-Apr-97 | 8.7 months |
| Sustiva | efavirenz, EFV | Bristol Myers-Squibb | 17-Sep-98 | 3.2 months |
| Viramune (Immediate Release) | nevirapine, NVP | Boehringer Ingelheim | 21-Jun-96 | 3.9 months |
| Viramune XR (Extended Release) | nevirapine, NVP | Boehringer Ingelheim | 25-Mar-11 | 9.9 months |
Protease Inhibitors (PIs)
| Brand Name | Generic Name | Manufacturer Name* | Approval Date | Time to Approval |
|---|---|---|---|---|
| Agenerase | amprenavir, APV (no longer marketed) | GlaxoSmithKline | 15-Apr-99 | 6 months |
| Aptivus | tipranavir, TPV | Boehringer Ingelheim | 22-Jun-05 | 6 months |
| Crixivan | indinavir, IDV, | Merck | 13-Mar-96 | 1.4 months |
| Fortovase | saquinavir (no longer marketed) | Hoffmann-La Roche | 7-Nov-97 | 5.9 months |
| Invirase | saquinavir mesylate, SQV | Hoffmann-La Roche | 6-Dec-95 | 3.2 months |
| Kaletra | lopinavir and ritonavir, LPV/RTV | Abbott Laboratories | 15-Sep-00 | 3.5 months |
| Lexiva | Fosamprenavir Calcium, FOS-APV | GlaxoSmithKline | 20-Oct-03 | 10 months |
| Norvir | ritonavir, RTV | Abbott Laboratories | 1-Mar-96 | 2.3 months |
| Prezista | darunavir | Tibotec, Inc. | 23-Jun-06 | 6 months |
| Reyataz | atazanavir sulfate, ATV | Bristol-Myers Squibb | 20-Jun-03 | 6 months |
| Viracept | nelfinavir mesylate, NFV | Agouron Pharmaceuticals | 14-Mar-97 | 2.6 months |
Fusion Inhibitors
| Brand Name | Generic Name | Manufacturer Name | Approval Date | Time to Approval |
|---|---|---|---|---|
| Fuzeon | enfuvirtide, T-20 | Hoffmann-La Roche & Trimeris | 13-Mar-03 | 6 months |
Entry Inhibitors - CCR5 co-receptor antagonist
| Brand Name | Generic Name | Manufacturer Name | Approval Date | Time to Approval |
|---|---|---|---|---|
| Selzentry | maraviroc | Pfizer | 06-August-07 | 8 months |
HIV integrase strand transfer inhibitors
| Brand Name | Generic Name | Manufacturer Name | Approval Date | Time to Approval |
|---|---|---|---|---|
| Isentress | raltegravir | Merck & Co., Inc. | 12--Oct-07 | 6 months |
*manufacturer/sponsor at time of approval
Generic drugs used in the Treatment of HIV Infection
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