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The Division of Residue Chemistry is responsible for the development and evaluation of analytical methods for drug residues in animal tissues, fluids, and feeds. These methods are for both use in agency regulatory programs and in the conduct of research studies. The division conducts metabolism and pharmacokinetic studies that help the CVM improve drug availability for minor uses and minor species. The research also aids center regulatory scientists by developing better models for drug bioavailability and fate and disposition. The division also is responsible for the review of drug residue diagnostic tests (screening tests). These evaluations determine if the products are accurately labeled and suitable for use by industry and regulators for testing animal-derived foods such as milk.
Mr. Michael H. Thomas is the Director of the division. He oversees the research activities of the two teams in the division and helps determine future research programs. Current interests include: 1) development of multiclass, multiresidue analytical methods, 2) discovery of tissue-fluid correlations of drug concentrations to allow surrogate monitoring, and 3) development of pharmacological models for drug bioavailability.
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