Trovan Information


On June 9, 1999, FDA issued a public health advisory to physicians concerning the risks of liver toxicity associated with the use of Trovan (trovafloxacin, an oral antibiotic) and Trovan-IV (alatrofloxacin, the intranvenous formulation of the drug). Trovan is an antibiotic used to treat many different types of infections. Trovafloxacin was approved for marketing in December, 1997, and became available on the market in February, 1998.   Based on new safety data related to serious liver injury, FDA is advising physicians that trovafloxacin should be reserved for use only in patients who meet the specific criteria outlined in the following public health advisory.

Do Not Buy Trovan Over the Internet

  • You should not buy Trovan over the Internet because you will bypass important safeguards designed to protect your health (and the health of others).
  • Trovan has special safety restrictions on how it is distributed to the public. Also, drugs purchased from foreign Internet sources are not the FDA-approved versions of the drugs, and they are not subject to FDA-regulated manufacturing controls or FDA inspection of manufacturing facilities. 

To learn more about buying drugs safely, please see 


FDA/Center for Drug Evaluation and Research
Last Updated: December 16, 2002

Originator: CDER/ORM
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