Comments on FDA Concept Paper

4/24/2003


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Table of Contents

Comments on FDA Concept Paper

General comments on risk management

Premarketing Risk Assessment - omission

Trial size – acute use / serious conditions

Trial size – chronic use

Subgroup analysis

Detection of unanticipated interactions

Biomarkers - caveats

Biomarkers - suggestions

Optimizing AE descriptions for signal detection - I

Optimizing AE descriptions for signal detection - II

Additional viewpoint – CIOMS-VI (working draft)

Thank you

Author: Sidney N Kahn

Home Page: http://www.fda.gov/cder/meeting/riskManagement.htm

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