In the GI Tract

• Sucralfate, some milk products, antacids, and oral iron preparations

• Omeprazole, lansoprazole,H2-antagonists

• Didanosine (givenas a buffered tablet)

• Cholestyramine

• Block absorptionof quinolones, tetracycline, and azithromycin

• Reduce absorptionof ketoconazole, delavirdine

• Reduces ketoconazole absorption

• Binds raloxifene,thyroid hormone, and digoxin

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