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Drug Development and Drug Interactions: Publications

2006

  • Lei Zhang, John M. Strong, Wei Qiu, Lawrence J. Lesko, and Shiew-Mei Huang. Scientific Perspectives on Drug Transporters and Their Role in Drug Interactions [PDF] [external link] Mol Pharm. 2006; 3(1), 62-69, Epub Jan 4 2006.

 2005

  • Andersson, T, Flockhart, DA, Goldstein, DB, Huang, S-M, Kroetz, D, Milos, P, Ratain, M, Thummel, K, Drug metabolizing enzymes- clinical utility of pharmacogenomic test.
    Clin Pharmacol Ther. 2005 Dec;78(6):559-81. [PDF]

  • Paine, MF, Ludington, SS, Chen, ML, Stewart, PW, Huang, S-M, Watkins, PB.
    Does sex influence proximal small intestinal or p-gp expression? Drug Metab Dispos. 2005 Mar;33(3):426-33. Epub 2004 Dec 17.

2004

  • Meadows, M. Preventing serious drug interactions [HTML] FDA Consumer, July-August 2004

  • Huang, S-M, Hall, SD, Watkins, P, Love, LA, Serabjit-Singh, C, Betz, JM, Hoffman, FA, Honig, P, Coates, PM, Bull, J, Chen, ST, Kearns, GL, Murray, MD. Drug interactions with herbal products & grapefruit juice: a conference report. Clin Pharmacol Ther. 2004, 75:1-12.

  • Shiew-Mei Huang and Lawrence J. Lesko  Drug-drug, drug-dietary supplement, and drug-citrus fruit and other food interactions — what have we learned? J Clin Pharmacol. 2004; 44:559-569. [PDF]

  • Gorski JC, Huang S-M, Pinto A, Hamman MA, Hilligoss JK, Zaheer NA, Desai M, Miller M, Hall, SD.  The effect of echinacea on cytochrome p450 activity in vivo. Clin Pharmacol Ther. 2004 Jan;75(1):89-100.

2003

  • Advisory Committee for Pharmaceutical Science  Clinical Pharmacology Section meeting minutes. April 20-21, 2003 (CYP3A classification and P-gp), Nov 17-18, 2003 (CYP2B6 and CYP2C8) [HTML], November 3, 2004 (Drug interaction concept paper) [PDF]

  • Hall SD, Wang Z, Huang, S-M, Hamman MA, Vasavada N, Adigun AQ, Hilligoss J, Miller M, Gorski, JC.  The interaction between St John’s wort and an oral contraceptive. Clin Pharmacol Ther. 2003 Dec;74(6):525-35.

2002

  • Yuan R, Madani S, Wei X, Reynolds K, and Huang S-M.  Evaluation of P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions.”  Drug Metab Dispos. 2002, Dec;30(12):1311-9. [PDF] PDF symbol

  • Wang Z, Hamman MA, Huang S-M, Lesko, LJ, Hall SD. Effect of St John's wort on the pharmacokinetics of fexofenadine. Clin Pharmacol Ther. 2002 Jun;71(6):414-20.

2001

  • Tucker G, Houston JB, and Huang S-M.  Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential — toward a consensus. Clin Pharmacol Ther. 2001 Aug;70(2):103-14; Br J Clin Pharmacol. 2001 Jul;52(1):107-17; Eur J Pharm Sci. 2001 Jul;13(4):417-28; Pharm Res. 2001, Aug;18(8):1071-80.

  • Wang Z, Gorski JC, Brater C, Huang S-M, Lesko, LJ, and Hall SD. The effects of St. John’s wort on human cytochrome P450 activity. Clin Pharmacol Ther. 2001 Oct;70(4):317-26.

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Date created: May 1, 2006

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