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The Office of Generic Drugs requested manufacturers of sixteen look-alike name pairs to voluntarily revise the appearance of their established names in order to minimize medication errors resulting from look-alike confusion. The project spanned a two month period beginning in March 2001 and ending in May 2001. In total, 142 letters were issued for 159 applications. The letters encouraged manufacturers to supplement their applications with revised labels and labeling that visually differentiated their established names with the use of "Tall Man" letters. The following is a list of the established names involved and the recommended revisions:
| Established
Name
|
Recommended Name
|
Acetohexamide
Acetazolamide
|
AcetoHEXAMIDE
AcetaZOLAMIDE
|
Bupropion
Buspirone
|
BuPROPion
BusPIRone
|
Chlorpromazine
Chlorpropamide
|
ChlorproMAZINE
ChlorproPAMIDE
|
Clomiphene
Clomipramine
|
ClomiPHENE
ClomiPRAMINE
|
Cyclosporine
Cycloserine
|
CycloSPORINE
CycloSERINE
|
Daunorubicin
Doxorubicin
|
DAUNOrubicin
DOXOrubicin
|
Dimenhydrinate
Diphenhydramine
|
DimenhyDRINATE
DiphenhydrAMINE
|
Dobutamine
Dopamine
|
DOBUTamine
DOPamine
|
Glipizide
Glyburide
|
GlipiZIDE
GlyBURIDE
|
Hydralazine
Hydroxyzine
|
HydrALAZINE
HydrOXYzine
|
|
Medroxyprogesterone
|
MedroxyPROGESTERone
|
Methylprednisolone
Methyltestosterone
|
MethylPREDNISolone
MethylTESTOSTERone
|
Nicardipine
Nifedipine
|
NiCARdipine
NIFEdipine
|
Prednisone
Prednisolone
|
PredniSONE
PrednisoLONE
|
Sulfadiazine
Sulfisoxazole
|
SulfADIAZINE
SulfiSOXAZOLE
|
Tolazamide
Tolbutamide
|
TOLAZamide
TOLBUTamide
|
Vinblastine
Vincristine
|
VinBLAStine
VinCRIStine
|
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Medication Errors
FDA/Center for Drug Evaluation and Research
Last Updated: May 8, 2002
Originator: OTCOM/DLIS
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