Drug Listing Procedures for Kits (Form FDA 2657)
When a product is made up of two or more components, as in a kit, a Form FDA 2657 must be used for the kit and each component. The first Form FDA 2657 will include information for the kit and the subsequent Form FDA 2657's will include information for each component of that kit. Indicate all numeric "zeros" as . Number each page on the lower right corner.
The first Form FDA 2657 will contain the following information regarding the entire kit:
Section 01
Name and Site Address of Firm
Col. 18 - S - Leave blank
Col. 19 - U - Leave blank
Col. 20-83 - Kit Trade Name
Col. 84-89 - National Drug Code Labeler Code
Col. 90-93 - National Drug Code Product Code
Col. 94-99 - FDA Application Number
Col. 100-105 - Report Date
Col. 106 - Type Rprt - Leave blank
Col. 107-111 - Type of Business
Col. 112-116 - Product Type
Col. 117 - BNDD - Leave blank
Col. 118 - Legal Status
Col. 119 - DEA Schedule
Col. 120-125 - Leave blank
Col. 126-140 - Basis of Concentration, in Col. 133 - Whole Numbers - enter 1, Col 134-137 - Decimal - leave blank, and in Col. 138-140 - Unit - enter KIT
Col. 141-143 - Dosage Form, enter KIT
Col. 144-147 - Routes of Administration, enter MISC
Col. 148-156 - Leave blank
Col. 157-158 - PT, enter 1 to represent the kit
Col. 159-164 - Initial Marketing Date
Col. 165-170 - Most Recent Marketing Date
Col. 171-176 - Discontinued Date - Leave blank
Section 03
Col. 18-20 - Leave blank
Col. 21-22 - Package Code
Col. 23-47 - Package Size
Col. 48-72 - Write the words "combination package"
Section 05
Col. 18-20 - Leave blank
Col. 21-22 - PT, enter 1
Col. 44-107 - Ingredient Information - If the kit has non-drug components, enter the words "non-drug components" on the first line. If the kit has drug components only, enter"Drugs only.".
Section 07
Col. 20-84 - Manufacturing information - Manufacturer/repacker's name, labeler code, state, and establishment registration number must be filled in or form will be returned.
Col. 85-99 - Leave blank
Information Pertaining to each drug Component in the Kit
Fill out a Form FDA 2657 for each drug component following instructions starting at the beginning of this chapter. Include the page number at the bottom right of the form. Subsequent Form FDA 2657's for the remaining parts in the kit will include the same type information as above. Exceptions are below:
Section 01
Col. 84-93 - National Drug Code Labeler and Product codes for the kit
Col. 100-105 - Report Date
Col. 126-140 - Basis of Concentration for the drug component
Col. 141-143 - Dosage Form of the drug component in the kit
Col. 144-147 - Routes of Administration for the drug component
Col. 157-158 - PT, enter 2 to represent the drug component
Section 05
Col. 20 - Enter Type of ingredient (A=Active, I=Inactive)
Col. 21-22 - PT, enter 2 to represent the drug component
Col. 44-107 - Ingredients for the drug component.
Col. 29-43 - Amount information for the ingredients
Enter the package size and package type information in Section 03.
Section 07
Col. 20-84 - Only use this section if the manufacturer of the first drug component is different than for the kit.