In the Spring of 1988 the Public Health Service sent this pamphlet to over 100 million households in the U.S.

When CDER began it consisted of six offices: Management (directed by Robert Bell), Compliance (Michels), Drug Standards (Rheinstein), Drug Evaluation I (Temple), Drug Evaluation II (James Bilstad), Epidemiology and Biostatistics (Faich), and Research Resources (Jerome Skelly). The Division of Antiviral Products was established in 1988 within the Office of Drug Evaluation II to assist with review of drugs for AIDS and other indications. The Office of the Center Director added two new staff offices in 1989. The Professional Development Staff developed and coordinated programs to assist with recruiting and training of Center staff, and the Pilot Drug Evaluation Staff fostered new ideas to streamline the drug approval process.