Temple became Director of the Office of Drug Research and Review and led the Divisions of Cardio-Renal Drug Products, Neuropharmacological Drug Products, Oncology and Radiopharmaceutical Drug Products, Surgical-Dental Drug Products, Drug Biology, Drug Chemistry, and Drug Analysis. Peter Rheinstein headed the Office of Drug Standards, which consisted of the Divisions of OTC Drug Evaluation, Biopharmaceutics, Generic Drugs, and Drug Advertising and Labeling. The Office of Epidemiology and Biostatistics, under Gerald Faich, was made up of the Division of Biometrics and the Division of Drug Experience. Finally, Elaine Esber led the Office of Biologics Research and Review.