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The NCDB consisted of five offices: New Drug Evaluation, Drugs, Biologics, Management, and Scientific Advisors and Consultants. The Office of New Drug Evaluation, directed by Robert Temple, was formed from the six Divisions in the Bureau of Drugs that reviewed NDAs. Jerome Halperin was the first Director of the Office of Drugs, which included the remaining Divisions from the Bureau of Drugs that conducted research and developed standards for the safety and effectiveness of drugs. The Office of Biologics, under John Petricciani, managed the Divisions from the Bureau of Biologics. Administrative functions were in the Office of Management, which Russell Abbott headed. The establishment of the Office of Scientific Advisors and Consultants, directed by Morris Schaeffer, facilitated scientific proficiency and research in drugs and biologics. Finally, the reorganization abolished the National Center for Antibiotics Analysis. Formed in 1968 from the old Division of Antibiotics and Insulin, the Center had been responsible for certification and testing of antibiotics. In 1981 the FDA proposed to phase out the certification program by late 1982, and the program ended on October 1, 1982.

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