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| A highlight in the Office's research was a study of ergot pharmacology conducted by Marvin R. Thompson. Initially, the Office had been concerned about decomposition of crude ergot; analysis had shown that this typically occurred during shipping. But the lack of knowledge of the pharmacology of ergot became obvious during this investigation. This led to the beginning of Thompson's work. In 1929 his paper was awarded the Ebert Prize of the American Pharmaceutical Association, bestowed annually for exceptional work in pharmacology. Thompson's paper was groundbreaking in many areas. He proposed modifications in the methods for assaying ergot, and showed that the USP standard for ergot could be improved by changing the preparation techniques. |
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