Curriculum Vitae

Vaccines and Related Biological Products Advisory Committee

Frank DeStefano, M.D., M.P.H.

Date of Birth: ----------------------
Place of Birth: ---------------------
Citizenship: -----------------------
Work Address

RTI International
2951 Flowers Rd.,
Suite 119
Atlanta , GA 30341
E-mail: fdestefano@rti.org

Educational:

----

A.B., Cornell University, Ithaca, New York

----

M.D., University of Pittsburgh, Pittsburgh, Pennsylvania

----

M.P.H. (Epidemiology), Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland

Residency:
1978 - 1979 Intern in Pediatrics, University of Rochester Hospitals, Rochester, New York
1980 - 1982 Preventive Medicine Resident, Centers for Disease Control (CDC), Atlanta, Georgia
Uniformed Service:
 

U.S. Public Health Service Commissioned Corps (1979-1992; 1996-2006)

Licensure:
 

Diplomate, National Board of Medical Examiners

Georgia Board of Medical Examiners --License No. ------

Certification:
 

Specialist in Public Health and General Preventive Medicine, the American Board of Preventive Medicine, 1986

Experience:
7/79-6/80

Epidemic Intelligence Service (EIS) Officer, Immunization Division, Bureau of State Services, CDC, Atlanta, Georgia

7/80-6/82

EIS Officer and Medical Epidemiologist, Epidemiologic Studies Branch (ESB), Family Planning Evaluation Division (FPED), Bureau of Epidemiology, CDC, Atlanta, Georgia

6/82-10/84

Medical Officer (Epidemiologist), Contraceptive Evaluation Branch, Center for Population Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland

11/84-7/88 Senior Epidemiologist, Agent Orange Projects, Division of Chronic Disease Control, Center for Environmental Health and Injury Control, CDC, Atlanta, Georgia
7/88-3/92

Medical Epidemiologist, Center for Chronic Disease Prevention and Health Promotion, CDC, Atlanta, Georgia
Chief, Epidemiology and Statistics Branch, Division of Diabetes Translation (7/88-7/90)

Cardiovascular Health Branch, Division of Chronic Disease Control and Community Intervention (2/91-3/92)

Chief, Surveillance Section, AIDS Surveillance Branch, Division of HIV/AIDS, National Center for Infectious Diseases, CDC (7/90-1/91)

3/92-1/96

Senior Epidemiologist, Division of Research and Education, Marshfield Clinic, Marshfield, Wisconsin
Chief, Section of Epidemiology
Director, Marshfield Epidemiologic Study Area ( MESA)

Chair, Marshfield Clinic Research Committee

1/96-4/2005

Medical Epidemiologist, National Immunization Program, CDC

10/2004-4/2005

Acting Chief, Immunization Safety Branch National Immunization Program, CDC

4/2005-1/2006

Acting Director, Immunization Safety Office
Office of the Chief Science Officer, CDC

1/2006-8/2006

Medical Epidemiologist
Director, Vaccine Safety Datalink (VSD) project
Immunization Safety Office, CDC

9/2006-current

Senior Research Epidemiologist
RTI International

Academic Appointments:
 

Adjunct Associate Professor, Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia (2/2002-3/2005)

 

Associate Clinical Professor, Department of Family and Community Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin (1/95-12/99)

  Clinical Assistant Professor, Department of Preventive Medicine, University of Wisconsin-Madison Medical School (5/92-8/98)
Foreign Languages:
  Italian
Honors:
 

Phi Beta Kappa Cornell University 1973
Alpha Omega Alpha University of Pittsburgh 1975

  USPHS Commissioned Corps Awards
  Outstanding Service Medal, 1989
Unit Commendation, 1990
Unit Commendation, 1991
Commendation Medal, 1991
Outstanding Unit Citation, 1997
Commendation Medal, 1999
Outstanding Unit Citation, 2004
 

Certificate of Recognition from the US-Egypt Cooperative Health Program, Egyptian Ministry of Health and U.S. Department of Health and Human Services, February 8, 1994

 

Centers for Disease Control and Prevention International Health Group Award for the Diabetes in Egypt Project, 1994

 

American Medical Association Physician’s Recognition Award in Continuing Medical Education, 1995

 

Highly Cited Author Award, RTI International, May 2007

Professional Organizations:
  Society for Epidemiologic Research
Fellow, American College of Preventive Medicine
USPHS Commissioned Officers Association
Teaching:
  Epidemiology (MGMP 520)
 

University of St. Thomas
MBA in Medical Group Management
Minneapolis , Minnesota
(Fall 1993 and Fall 1995)

 

Programma di Formazione in Epidemiologia Applicata (PRO.F.E.A.)
(Field epidmiology training program in the Campania region of Italy)
Istituto Superiore di Sanita= ( Rome) and Campania Region ( Naples)
Ischia , Italy , September 8-19, 1997

Presentations:
 

Pneumococcal and Influenza Vaccines, 15th Immunization Conference, Denver, Colorado, March 10-13, 1980

 

Simultaneous Administration of Influenza and Pneumococcal Vaccines, 20th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), New Orleans, Louisiana, September 21-25, 1980

 

An Influenza B Outbreak at a Boys Boarding School: Estimate of Vaccine Efficacy, 20th ICAAC, New Orleans, Louisiana, September 21-25, 1980

 

The Safety of Tubal Sterilization, Annual EIS Conference, Atlanta, Georgia, April 20-24, 1981

 

The Safety of Tubal Sterilization Operations, Annual Meeting of the American Public Health Association (APHA), Los Angeles, California, November 1-5, 1981

 

Pregnancies and Other Long-Term Sequelae Following Tubal Sterilization, Annual Meeting of APHA, Los Angeles, California, November 1-5, 1981

 

The Safety of Tubal Sterilization, American Association of Gynecologic Laparoscopists (AAGL) Tenth Annual Meeting, Phoenix, Arizona, November 4-8, 1981

 

Menstrual Changes after Tubal Sterilization: 2-year Follow-up of 2,456 Women, AAGL Eleventh Annual Meeting, San Diego, California, November 10-14, 1982

 

Epidemiological Studies of IUD Safety, Medical Data Base Conference, Washington, D.C., October 20, 1983

 

Long-Term Evaluation of Menstrual Function After Tubal Sterilization, Association of Planned Parenthood Professionals 22nd Annual Scientific Meeting, San Antonio, Texas, November 3, 1984

 

Long_Term Evaluation of Menstrual Function After Tubal Sterilization, AAGL Thirteenth Annual Meeting, Los Vegas, Nevada, November 8, 1984

 

Epidemiologic Studies of Vietnam Veterans, Veterans Administration Agent Orange Continuing Education Workshop, Washington, D.C., August 21, 1985

 

Automated Semen Analysis in Large Epidemiologic Studies, American Society of Andrology 12th Annual Meeting, Denver, Colorado, March 7, 1987

 

Behavioral Risk Factor Prevalence in Army Veterans, Prevention 87: Delivering Preventive Services, Atlanta, Georgia, April 11, 1987

 

The Centers for Disease Control Epidemiological Studies of Vietnam Veterans, American College of Epidemiology Annual Meeting, Ann Arbor, Michigan, October, 1988

 

Semen Characteristics of Vietnam Veterans, American Society of Andrology 14th Annual Meeting, New Orleans, Louisiana, April 15, 1989

 

Surveillance: Information for Action, 1989 CDC Diabetes Translation Conference, Atlanta, Georgia, May 23, 1989

 

Diabetes Objectives for the Year 2000, 1989 CDC Diabetes Translation Conference, Atlanta, Georgia, May 24, 1989

 

Preventing Diabetes Complications, American Diabetes Association Fiftieth Annual Meeting, Atlanta, Georgia, June 16, 1990

 

Hospitalizations Related to Diabetes Mellitus, United States, 1980-1987, American Diabetes Association Fiftieth Annual Meeting, Atlanta, Georgia, June 17, 1990

  Comparison of Coronary Heart Disease Mortality Risk Between Black and White Persons with Diabetes, American College of Epidemiology 10th Annual Scientific Meeting, Atlanta, Georgia, November 7, 1991
 

Trends in Nonfatal Coronary Heart Disease, 32nd Annual Conference on Cardiovascular Disease Epidemiology, American Heart Association, Memphis, Tennessee, March 20, 1992

 

Nonfatal Coronary Heart Disease Trends Among Women in the United States, 1980-89, American College of Epidemiology 11th Annual Scientific Meeting, Bethesda, Maryland, September 17, 1992

 

Dairy Products and Lipoproteins in Children. Third International Conference on Preventive Cardiology. Oslo, Norway, June 29, 1993

 

Cholesterol Screening in Children and Young Adults. Eighth National Conference on Chronic Disease Prevention and Control. Kansas City, Missouri, November 18, 1993.

  The Marshfield Epidemiologic Study Area. First Wisconsin Epidemiologic Research Symposium. Madison, Wisconsin, April 8, 1994.
 

Population-based Epidemiology of Carpal Tunnel Syndrome. Annual Scientific Meeting of the American College of Rheumatology. Minneapolis, Minnesota, October 25, 1994.

 

Determinants of Serum Lipid and Lipoprotein Concentrations in Children. Second Wisconsin Epidemiology Research Symposium. Madison, Wisconsin, March 20, 1995.

 

Timing of Hepatitis B Vaccination and Risk of Insulin-Dependent Diabetes Mellitus. Thirteenth International Conference on Pharmacoepidemiology. Lake Buena Vista, Florida, August 26, 1997.

 

Study of Vaccination and Risk of Type 1 Diabetes in the Vaccine Safety Datalink. Workshop on Childhood Immunizations and Insulin Dependent Diabetes Mellitus. The Institute for Vaccine Safety, Johns Hopkins University, Baltimore, Maryland, March 20, 1998.

  Opportunities for Population-based Clinical Research Using Data from Managed Care Organizations. Institute of Medicine Forum on Emerging Infections. Washington, DC, March 23, 1998.
 

Vaccine Safety Datalink: Status Report. Workshop on an Evaluation of the Possible Role of Vaccines and Infectious Diseases in Insulin Dependent (Type 1) Diabetes Mellitus. National Institutes of Health, Bethesda, Maryland, May 15, 1998.

 

Opportunities for immunization research in managed care organizations: the Vaccine Safety Datalink. 32 nd National Immunization Conference, Atlanta, Georgia, July 23, 1998

 

Current concepts in vaccine safety. Symposium on Current Concepts in Childhood Immunization. Strategic Implications International, San Diego, California, September 24, 1998

 

DTP and MMR vaccines are not associated with risk of asthma, 38th ICAAC, San Diego, California, September 26, 1998

 

Hepatitis B vaccine safety: Research and technical issues. National Hepatitis Coordinators Conference, Tucson, Arizona, May 26, 1999

  Infant vaccinations and risk of asthma in childhood, 15 th International Conference on Pharmacoepidemiology, Boston, Massachusetts, August 29, 1999
 

Hepatitis B and Hib vaccinations and type 1 diabetes, 39th ICAAC, San Francisco, California, September 26, 1999

 

Infant vaccinations and risk of asthma in childhood, 39th ICAAC, San Francisco, California, September 26, 1999

 

Chronic oral infection as a risk factor for cardiovascular disease, Continuing Education Meeting on Interactions between Oral and General Health, Zurich, Switzerland, November 13, 1999

 

The Vaccine Safety Datalink Project, Health Care Databases and Research: A Symposium on the Power and Perils of health Data Used in Epidemiologic and Economic Research, Chapel Hill, North Carolina, April 14, 2000.

 

Hepatitis B vaccination and demyelinating diseases: an interim analysis from the Vaccine Safety Datalink. 16 th International Conference on Pharmacoepidemiology, Barcelona, Spain, August 23, 2000.

 

Hepatitis B and Hib vaccines are not associated with increased risk of type 1 diabetes. 40 th ICAAC, Toronto, Canada, September 19, 2000.

  Childhood vaccinations and type 1 diabetes. 17 th International Conference on Pharmacoepidemiology, Toronto, Canada, August 24, 2001.
 

Safety of Hepatitis B vaccine: Infants to adults. 41 st ICAAC, Chicago, Illinois, December 17, 2001.

Hepatitis B vaccine and risk of demyelinating diseases in adults. Institute of Medicine Immunization Safety Review Committee, Washington, DC, March 11, 2002

The epidemiology of autism. Eighth Annual Maternal and Child Health Epidemiology Conference. Tampa, Florida, December 12, 2002.

Influenza vaccine and multiple sclerosis. Institute of Medicine Immunization Safety Review Committee, Washington, DC, March 13, 2003.

Long-term risk of intussusception following Rhesus-human reassortant rotavirus tetravalent vaccine (RRV-TV). 43 rd ICAAC, Chicago, Illinois, September 17, 2003.

Age at First Measles-Mumps-Rubella Vaccination in Children with Autism and School-Matched Control Subjects. Institute of Medicine Immunization Safety Review Committee, Washington, DC, February 9, 2004.

Vaccine safety assessment and policy implications. Preventive Medicine 2004: American College of Preventive Medicine Annual Conference. Orlando, Florida, February 20, 2004.

Age at First MMR Vaccination Among Children with Autism and School-Matched Controls in Metropolitan Atlanta. International Meeting for Autism Research, Sacramento, CA, May 7, 2004.

Determining risk of multiple sclerosis after hepatitis B vaccine: Time since vaccination and source of data. 20 th International Conference on Pharmacoepidemiology, Bordeaux, France, August 24, 2004.

VSD studies that utilized iterative analyses. Institute of Medicine Committee on Review of NIP’s Research Procedures and Data Sharing Program, Washington, DC, October 21, 2004.

Immunization Safety Activities at the United States Centers for Disease Control and Prevention. 6 th Meeting of the WHO Steering Committee on Immunization Safety, Geneva, Switzerland, September 21, 2005.

Common and rare events: The process for monitoring and evaluating vaccine safety. Clinical Vaccinology Course, National Foundation for Infectious Diseases. Atlanta, Georgia, November 4, 2006.

Safety Profile of Pneumococcal Conjugate Vaccines. World Health Organization Global Advisory Committee on Vaccine Safety, Geneva, Switzerland, November 30, 2006.

Publications:

 

DeStefano F , Coulehan JL, Wiant MK: Blood pressure survey on the Navajo Indian reservation. Am J Epidemiol 1979;109:335-45

Peterson HB, Greenspan JR, DeStefano F, Ory HW, Layde PM. The impact of laparoscopy on tubal sterilization in United States hospitals, 1970 and 1975 to 1978. Am J Obstet Gynecol 1981;140:811-4

Peterson HB, Greenspan JR, Ory HW, DeStefano F. Tubal sterilization mortality surveillance, United States, 1978-1979. Adv Plan Parent 1981;16:71-6

DeStefano F , Goodman RA, Noble GR, McClary GD, Smith SJ, Broome CV. Simultaneous administration of influenza and pneumococcal vaccines. JAMA 1982;247:2551-4

DeStefano F . An outbreak of Influenza B at an Indiana boarding school: estimate of vaccine efficacy. Pub Health Rep 1982;97:269-72

DeStefano F , Greenspan JR, Ory HW, Peterson HB, Maze JM, Smith JC. Demographic trends in tubal sterilization: United States, 1970-1978. Am J Public Health 1982;72:480-4

DeStefano F , Peterson HB, Ory HW, Layde PM. Oral contraceptives and postoperative venous thrombosis. Am J Obstet Gynecol 1982;143:227-8

DeStefano F , Peterson HB, Layde PM, Rubin GL. Risk of ectopic pregnancy following tubal sterilization. Obstet Gynecol 1982;60:326-30

Peterson HB, DeStefano F, Greenspan JR, Ory HW. Mortality risk associated with tubal sterilization in United State Hospitals. Am J Obstet Gynecol 1982;143:125-9

Peterson HB, Greenspan JR, DeStefano F, Ory HW. Deaths associated with laparoscopic sterilization in the United States, 1977-79. J Reprod Med 1982;27:345-7

Dicker RC, Greenspan JR, Strauss LT, Cowart MR, Scally MJ, Peterson HB, DeStefano F, Rubin GL, Ory HW. Complications of abdominal and vaginal hysterectomy among women of reproductive age in the United States. Am J Obstet Gynecol 1982;144:841-8

DeStefano F , Greenspan JR, Dicker RC, Peterson HB, Strauss LT, Rubin GL. Complications of interval laparoscopic tubal sterilization. Obstet Gynecol 1983;61:153-8

DeStefano F , Huezo CM, Peterson HB, Rubin GL, Layde PM, Ory HW. Menstrual changes after tubal sterilization. Obstet Gynecol 1983;62:673-81

DeStefano F , Stadel BV, Layde PM, Ory HW, Peterson HB. Oral contraceptives and postoperative venous thrombosis [letter]. Am J Obstet Gynecol 1983;145:773-4

Peterson HB, DeStefano F, Rubin GL, Greenspan JR, Lee NC, Ory HW. Deaths attributable to tubal sterilization in the United States, 1977 to 1981. Am J Obstet Gynecol 1983;146:131-6

Huezo CM, DeStefano F, Rubin GL, Ory HW. Risk of wound and pelvic infection after laparoscopic tubal sterilization: instrument disinfection versus sterilization. Obstet Gynecol 1983;61:598-602

Peterson HB, Lubell I, DeStefano F, Ory HW. The safety and efficacy of tubal sterilization: an international overview. Int J Gynaecol Obstet 1983;21:139-44

Layde PM, Peterson HB, Dicker RC, DeStefano F, Rubin GL, Ory HW. Risk factors for complications of interval tubal sterilization by laparotomy. Obstet Gynecol 1983;62:180-4

DeStefano F , Peterson HB. Ectopic pregnancy after sterilization [letter]. JAMA 1984;251:1432

Ory HW, Rubin GL, Jones V, Wingo P, DeStefano F, Peterson H, et al. Mortality among young black women using contraceptives. JAMA 1984;251:1044-8

DeStefano F , Perlman JA, Peterson HB, Diamond EL. Long-term risk of menstrual disturbances after tubal sterilization. Am J Obstet Gynecol 1985;152:835-41

Peterson HB, Grubb GS, DeStefano F, Rubin GL. Complications of tubal sterilization. In: Siegler AM, editor. The fallopian tube: basic studies and clinical contributions. Mount Kisco: Futura Publishing Company, Inc., 1986;329-46.

Pollock DA, Boyle CA, DeStefano F, Moyer LA, Kirk ML. Underreporting of alcohol-related mortality on death certificates of young U.S. Army Veterans. JAMA 1987;258:345-8

DeStefano F , Annest JL, Kresnow M, Schrader SM, Katz DF. Semen Characteristics of Vietnam Veterans. Reprod Toxicol 1989;3:165-73

Joesoef MR, Wetterhall SF, DeStefano F, Stroup NE, Fronek A. The association of peripheral arterial disease with hostility in a young, healthy Veteran population. Psychosom Med 1989;51:285-9

O'Brien TR, Flanders WD, Decoufle P, Boyle CA, DeStefano F, Teutsch S. Are racial differences in the prevalence of diabetes in adults explained by differences in obesity? JAMA 1989;262:1485-8

Freedman DS, Strogatz DS, Eaker E, Joesoef MR, DeStefano F. Differences between black and white men in correlates of high density lipoprotein cholesterol. Am J Epidemiol 1990;132:656-69

Ford ES, DeStefano F. Risk factors for mortality from all causes and from coronary heart disease among people with diabetes: findings from the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study. Am J Epidemiol 1991;133:1220-30

Ring AR, DeStefano F, Geiss L, Lyons A, Olson D, Peddicord M. Centers for Disease Control: community-based diabetes control programs and the Diabetes Translation Center. In: Davidson JK, editor. Clinical diabetes mellitus...: a problem oriented approach, 2nd ed. New York: Thieme Medical Publishers, 1991:728-37

Freedman DS, O'Brien TR, Flanders WD, DeStefano F, Barboriak JJ. Relation of serum testosterone levels to high density lipoprotein cholesterol and other characteristics in men. Arterioscler Thromb 1991;11:307-15

Mili F, Flanders WD, Boring JR, Annest JL, DeStefano F. The associations of race, cigarette smoking, and smoking cessation to measures of the immune system in middle-aged men. Clin Immunol and Immunopathol 1991;59:187-200

Wetterhall SF, Olson DR, DeStefano F, et al. Trends in diabetes and diabetic complications, 1980-1987. Diabetes Care 1992;15:960-7

Mili F, Flanders WD, Boring JR, Annest JL, DeStefano F. The associations of alcohol drinking and drinking cessation to measures of the immune system in middle-aged men. Alcohol Clin Exp Res 1992;16:688-94

Boyle CA, Khoury MJ, Katz DF, Annest JL, Kresnow M, DeStefano F, Schrader SM. The relation of computer-based measures of sperm morphology and motility to male infertility. Epidemiology 1992;3:239-46

DeStefano F , Ford ES, Newman J, et al. Risk factors for coronary heart disease mortality among persons with diabetes. Ann Epidemiol 1993;3:27-34

DeStefano F , Newman J. Comparison of coronary heart disease mortality risk between black and white people with diabetes. Ethnicity Dis 1993;3:145-51

DeStefano F , Anda RF, Kahn HS, Williamson DF, Russell CM. Dental disease and risk of coronary heart disease and mortality. Br Med J 1993;306:688-91

DeStefano F , Merritt RK, Anda RF, Casper ML, Eaker ED. Trends in nonfatal coronary heart disease in the United States, 1980 through 1989. Arch Intern Med 1993;153:2489-94

Newman JM, DeStefano F, Valway SE, German RR, Muneta B. Diabetes-associated mortality in Native Americans. Diabetes Care 1993;16:297-9

Giles WH, Anda RF, Jones DH, Serdula MK, Merritt RK, DeStefano F. Recent trends in the identification and treatment of high blood cholesterol by physicians: progress and missed opportunities. JAMA 1993;269:1133-8

Giles WH, Anda RF, Jones DH, Serdula MK, Merritt RK, DeStefano F. Cholesterol screening in young adults [letter]. JAMA 1993;270:1546-7

DeStefano F , Berg RL, Griese GG, Jr. Determinants of serum lipid and lipoprotein concentrations in children. Epidemiology 1995;6:446-9.

Herman WH, Aubert RE, Englegau MM, Kenny SJ, Gunther EW, Malarcher AM, Brechner RM, Wetterhall SF, DeStefano F, et al. Diabetes mellitus in Egypt: Risk factors and prevalence. Diabetic Medicine 1995; 12:1126-31.

Nordstrom DL, DeStefano F. Evaluation of Wisconsin legislation on smoking in restaurants. Tobacco Control 1995;4:125-8

DeStefano F . Effects of Agent Orange exposure (invited letter). JAMA 1995;273:1494

DeStefano F , Eaker ED, Broste SD, Nordstrom DL, Peissig PL, Vierkant RA, Konitzer KA, Gruber RL, Layde PM. Epidemiologic research in an integrated regional medical care system: the Marshfield Epidemiologic Study Area. Journ Clin Epidemiol 1996;49:643-52.

DeStefano F , Nordstrom DL, Vierkant RA. Longterm symptoms outcomes of Carpal Tunnel Syndrome and its treatment. J Hand Surg 1997;22A:200-10.

Nordstrom DL, Vierkant RA, DeStefano F, Layde PM. Risk factors for Carpal Tunnel Syndrome in a general population. Occup Environ Med 1997; 54:734-40.

Nordstrom DL, Vierkant RA, DeStefano F, Layde PM. Incidence of diagnosed Carpal Tunnel Syndrome in a general population. Epidemiology 1998;9:342-5.

Orejarena LA, Vidaillet H, DeStefano F, et al. Paroxysmal supraventricular tachycardia in the general population. J Am Coll Cardiol 1998; 31:150-7.

Chen RT, DeStefano F. Vaccine adverse events: causal or coincidental? [invited Commentary] Lancet 1998;351:611-2.

Chen RT, DeStefano F. Vaccine safety [letter]. Lancet 1998;352:63-4.

 Herman WH, Aubert RE, Engelgau MM, Thompson TJ, Ali MA, Sous ES, Hegazy M, Badran A, Kenny SJ, Gunter EW, Malarcher AM, Brechner RJ, Wetterhall SF, DeStefano F, Smith PJ, Habib M, abd el Shakour S, Ibrahim AS, el Behairy EM. Diabetes mellitus in Egypt: glycaemic control and microvascular and neuropathic complications. Diabet Med 1998;15:1045-1051.

Mullooly J, Drew L, DeStefano F, et al. Quality of HMO vaccination data bases used to monitor childhood vaccine safety. Am J Epidemiol 1999;149:186-94.

Jackson LA, Benson P, Sneller VP, Butler JC, Thompson RS, Chen RT, Lewis LS, Carlone G, DeStefano F, Holder P, Lezhava T, Williams WW. Safety of revaccination with pneumococcal polysaccharide vaccine. JAMA 1999;281:243-8.

 Gargiullo PM, Kramarz P, DeStefano F, Chen RT. Priciples of epidemiological research on drug effects [letter]. Lancet 1999;353:501.

DeStefano F , Chen RT. Negative association between MMR and autism [Commentary] Lancet 1999;353:1987-8.

Davis RL; Rubanowice D; Shinefield HR; Lewis N; Gu D; Black SB; DeStefano F; Gargiullo P; Mullooly JP; Thompson RS; Chen RT. Immunization levels among premature and low-birth-weight infants and risk factors for delayed up-to-date immunization status. JAMA 1999;282:547-53.

Izurieta H, Thompson WW, Kramarz P, Shay DK, Davis RL, DeStefano F, Black S, Shinefield H, Fukuda K. Impact of influenza on the rates of respiratory disease hospitalizations among young children. N Engl J Med 2000;342:232-9.

 DeStefano F . Opportunities for population-based clinical research using data from managed care organizations. In: Davis JR, editor. Managed care systems and emerging infections. Washington, DC: National Academy Press, 2000;16-8.

 Zoch TW, Desbiens NA, DeStefano F, Stueland DT, Layde PM. Short- and long-term survival after cardiopulmonary resuscitation. Arch Intern Med 2000;160:1969-73.

Kramarz P, DeStefano F, Gargiullo P, Davis RL, Chen RT, Mullooly JM, Black SB, Bohlke K, Ward JI, Marcy MM, Okoro CA. Influenza vaccination in children with asthma in Health Maintenance Organizations. Vaccines 2000;18:2288-94.

Chen RT, DeStefano F, Davis RL, et al. The Vaccine Safety Datalink: Immunization research in health maintenance organizations in the USA. WHO Bulletin 2000;78:186-94.

 Kramarz P, DeStefano F, Gargiullo P, Davis RL, Chen RT, Mullooly JM, Black SB, Shinefield HR, Bohlke K, Ward JI, Marcy SM. Does influenza vaccination exacerbate asthma? Arch Fam Med 2000;9:617-23.

Chen RT, Mootrey G, DeStefano F. Safety of routine childhood vaccinations: An epidemiological review. Paediatr Drugs 2000;2:273-90.

Belay ED, Holman RC, Clarke MJ, DeStefano F, et al. The incidence of Kawasaki syndrome in West Coast health maintenance organizations. Pediatr Infect Dis J 2000;19:828-32.

Davis RL, Kramarz P, Bohlke K, Benson P, Thompson RS, Mullooly J, Black S, Shinefield H, Lewis E, Ward J, Marcy SM, Eriksen E, DeStefano F, Chen RT. Measles-mumps-rubella and other measles-containing vaccines do not increase the risk for inflammatory bowel disease. Arch Pediatr Adol Med 2001;155:354-9.

DeStefano F , Verstraeten T. Multiple Sclerosis (letter). N Engl J Med 2001;344:381.

Kramarz P, DeStefano F, Gargiullo P, Chen RT, Lieu TA, Davis RL, Mullooly JM, Black SB, Shinefield HR, Bohlke K, Ward JI, Marcy SM. Does influenza vaccination exacerbate asthma? J Pediatr 2001;138:306-10.

Chen RT, DeStefano F, Pless R, Mootrey G, Kramarz P, Hibbs B. Challenges and controversies in immunization safety. Infect Dis Clinics North America 2001;15:21-39.

Kramarz P, France EK, DeStefano F, et al. Population-based study of rotavirus vaccination and intussusception. Pediatr Infect Dis J 2001;20:410-6.

DeStefano F . More evidence to reassure physicians and parents about vaccination (commentary). West J Med 2001;174:390-1.

DeStefano F . The Vaccine Safety Datalink Project. Pharmacoepidemiol Drug Safety 2001;10:403-6.

Nordstrom DL, Krauska M, DeStefano F, Zahm S. Ability to trace migrant farmworkers ten years after initial identification in a northern state ( Wisconsin). Am J Ind Med 2001;40:592-5.

Jackson LA, Austin G, Chen RT, Stout R, DeStefano F, Gorse GJ, Weniger BG, Newman FK, Yu O. Safety and immunogenicity of varying doses of trivalent inactivated influenza vaccine administered by needle-free injectors. Vaccine 2001;19(32):4703-9

Barlow WE, Davis RL, Glasser JW, Rhodes PH, Thompson RS, Mullooly JP, Black SB, Shinefield HR, Ward JI, Marcy SM, DeStefano F, Chen RT. The risk of seizures after reeipt of whole-cell pertussis or measles, mumps, and rubella vaccine. N Engl J Med 2001;345:656-61.

DeStefano F , Chen RT. Autism and MMR vaccination: controversy laid to rest? CNS Drugs 2001;15:831-7.

Chen RT, Pless R, DeStefano F. Epidemiology of autoimmune reactions induced by vaccination. J Autoimmunity 2001;16:309-18.

DeStefano F . Vaccines and autism. Pediatr Infect Dis J 2001;20:887-8.

Lewis E, Shinefield HR, Woodruff BA, Black SB, DeStefano F, Chen RT. Safety of neonatal hepatitis B vaccine administration. Pediatr Infect Dis J 2001;20:1051-6.

DeStefano F . Childhood vaccinations, vaccination timing, and risk of type 1 diabetes mellitus. Pediatrics 2001;108 (6). URL: http://www.pediatrics.org/cgi/content/full/108/6/e112.

DeStefano F . Childhood vaccinations and type 1 diabetes [letter]. Pediatrics 2002. URL: http://www.pediatrics.org/cgi/eletters/108/6/e112.

Mullooly JP, Pearson J, Drew L, Schuler R, Maher J, Gargiullo P, DeStefano F, Chen R. Wheezing lower respiratory disease and vaccination of full-term infants. Pharmacoepidemiol Drug Safety 2002;11:21-30.

DeStefano F , Gu D, Kramarz P, et al. Childhood vaccinations and risk of asthma. Pediatr Infect Dis J 2002;21:498-504.

Gonzalez IM, Averhoff FM, Massoudi MS, Yusuf H, DeStefano F, et al. Hepatitis B vaccination among adolescents in three large health maintenance organizations. Pediatrics 2002; 110:929-34.

Black S, Lewis E, Shinefield H, Fireman B, Ray P, DeStefano F, Chen R. Lack of association between receipt of conjugate Haemophilus influenzae type b vaccine (HBOC) in infancy and risk of type1 (juvenile onset) diabetes: long term follow-up of the HBOC Efficacy Trial cohort. Pediatr Infect Dis J 2002;21(6):568-9.

DeStefano F , Thompson WW. MMR vaccination and autism: is there a link? Expert Opin Drug Saf 2002;1:115-20.

DeStefano F . MMR vaccine and autism: a review of the evidence for a causal association. Molecular Psychiatry 2002;7(s2):S51-S52.

DeStefano F , Verstraeten T, Chen RT. Hepatitis B vaccine and risk of multiple sclerosis. Expert Review of Vaccines 2002;1:461-6.

Verstraeten T, DeStefano F, Chen RT, Miller E. Vaccine safety surveillance using large linked databases: opportunities, hazards and proposed guidelines. Expert Rev Vaccine s 2003;289-97.

DeStefano F , Verstraeten T, Jackson LA, et al. Vaccinations and risk of central nervous system demyelinating diseases in adults. Arch Neurol 2003;60:504-9.

Verstraeten T, Jumaan AO, Mullooly JP, Seward JF, Izurieta HS, DeStefano F, Black SB, Chen RT. A Retrospective Cohort Study of the Association of varicella vaccine failure with asthma, steroid use, age at vaccination, and measles-mumps-rubella vaccination. Pediatrics 2003;112:e98 –e103.

Bohlke K, Davis RL, Marcy SM, Braun MM, DeStefano F, et al. The risk of anaphylaxis following vaccination of children and adolescents. Pediatrics 2003;112:815-20.

Verstraeten T, Davis RL, DeStefano F, et al. Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases. Pediatrics 2003;112:1039-48.

Haber P, DeStefano F. Letter to the editor [Influenza vaccine and Guillain Barre Syndrome]. Clin Immunol 2003;109:359.

DeStefano F , Karapurkar T, Thompson WW, Yeargin-Allsopp M, Boyle C. Age at first measles-mumps-rubella vaccination in children with autism and school-matched controls: a population-based study in metropolitan Atlanta. Pediatrics 2004;113:259-66.

Spector L, Groves F, DeStefano F, et al. Medically recorded allergies and the risk of acute lymphoblastic leukaemia. Europ J Cancer 2004;40:579-84.

DeStefano F , Thompson WW. MMR vaccine and autism: An update of the scientific evidence. Expert Rev Vaccines 2004;3:11-14.

Maher JE, Mullooly JP, Drew L, DeStefano F. Infant vaccinations and childhood asthma among full-term infants. Pharmacoepidemiol Drug Safety 2004;13:1-9.

Bohlke K, Davis RL, DeStefano F, et al. Epidemiology of anaphylaxis among children and adolescents enrolled in a health maintenance organization. J Allergy Clin Immunol 2004;113: 536-42.

Varrichio F, Iskander J, DeStefano F, et al. Understanding vaccine safety information from the Vaccine Adverse Event Reporting System. Pediatr Infect Dis J, 2004;23:287–94.

Mullooly J, Drew L, DeStefano F, et al. Quality assessments of HMO diagnosis databases used to monitor childhood vaccine safety. Methods Inf Med 2004;43:163-70.

Zhou W, Pool P, DeStefano F, et al. A potential signal of Bell's palsy after parenteral inactivated influenza vaccines: reports to the Vaccine Adverse Event Reporting System (VAERS) - United States, 1991-2001. Pharmacoepidemiol Drug Safety 2004;13:505-10.

Zhou W, Pool P, DeStefano F, et al. Reply to Editorial [Clinical judgment, common sense and adverse reaction reporting]. Pharmacoepidemiol Drug Safety 2004;13:515-7.

Eriksen EM, Perlman JA, Miller A, Marcy SM, Lee H, Vadheim C, Zangwill KM, Chen RT, DeStefano F, Lewis E, Black S, Shinefield H, Ward JI. Lack of association between hepatitis B birth immunization and neonatal death: a population-based study from the vaccine safety datalink project. Pediatr Infect Dis J. 2004;23:656-62.

Haber P, DeStefano F, Angulo FJ, et al. Guillain-Barre Syndrome following influenza vaccination. JAMA 2004;292:2478-81.

Thompson WW, DeStefano F, Chen RT. Letter to the Editor [re: The evidence for the safety of thimerosal in newborn and infant vaccines]. Vaccine 2004;23:281-2.

Mandell DS, Thompson WW, Weintraub ES, DeStefano F, Blank MB. Trends in diagnosis rates for autism and ADHD at hospital discharge in the context of other psychiatric diagnoses. Psychiatric Services 2005;56:56–62.

DeStefano F , Weintraub ES, Chen RT. Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study [letter]. Neurology 2005;64:1317.

Verstraeten T, Davis R, Destefano F. Immunity to tetanus is protective against the development of multiple sclerosis. Med Hypotheses 2005;65(5):966-9.

DeStefano F . Vaccine Safety. Medscape Public Health and Prevention. 2006;4(2): http://www.medscape.com/viewarticle/542679 [invited article for Perspectives in Prevention From the American College of Preventive Medicine].

Jackson LA, Neuzil KM, Baggs J, Davis RL, Black S, Yamasaki KM, Belongia E, Zangwill KM, Mullooly J, Nordin J, Marcy SM, DeStefano F. Compliance with the recommendations for 2 doses of trivalent inactivated influenza vaccine in children less than 9 years of age receiving influenza vaccine for the first time: a Vaccine Safety Datalink study. Pediatrics. 2006 Nov;118(5):2032-7.

Hambidge SJ, Glanz JM, France EK, McClure D, Xu S, Yamasaki K, Jackson L, Mullooly JP, Zangwill KM, Marcy SM, Black SB, Lewis EM, Shinefield HR, Belongia E, Nordin J, Chen RT, Shay DK, Davis RL, DeStefano F; Vaccine Safety Datalink Team. Safety of trivalent inactivated influenza vaccine in children 6 to 23 months old. JAMA. 2006 Oct 25;296(16):1990-7.

Neuzil KM, Jackson LA, Nelson J, Klimov A, Cox N, Bridges CB, Dunn J, DeStefano F, Shay D. Immunogenicity and reactogenicity of 1 versus 2 doses of trivalent inactivated influenza vaccine in vaccine-naive 5-8-year-old children. J Infect Dis. 2006 Oct 15;194(8):1032-9. Epub 2006 Sep 11.

DeStefano F , Weintraub ES, Chen RT. Hepatitis B vaccine and risk of multiple sclerosis [letter]. Pharmacoepidemiol Drug Safety 2007;16:705–8.

Corporate Authored Publications:

 

The Centers for Disease Control Cancer and Steroid Hormone Study. Long-term oral contraceptive use and the risk of breast cancer. JAMA 1983;249:1591-5 ( Project Associate)

The Centers for Disease Control Cancer and Steroid Hormone Study. Oral contraceptive use and the risk of ovarian cancer. JAMA 1983;249:1596-9 ( Project Associate)

The Centers for Disease Control Cancer and Steroid Hormone Study. Oral contraceptive use and the risk of endometrial cancer. JAMA 1983;249:1600-4 ( Project Associate)

The Centers for Disease Control Vietnam Experience Study. Postservice mortality among Vietnam Veterans. JAMA 1987;257:790-5 ( Co-author)

The Centers for Disease Control Vietnam Experience Study. Health Status of Vietnam Veterans: I. Psychosocial characteristics. JAMA 1988;259:2701-7 ( Principal Author)

The Centers for Disease Control Vietnam Experience Study. Health Status of Vietnam Veterans: II. Physical Health. JAMA 1988;259:2708-14 ( Principal Author)

The Centers for Disease Control Veterans Health Studies. Serum 2,3,7,8-tetrachlorodibenzo-p-dioxin levels in U.S. Army Vietnam-Era Veterans. JAMA 1988;260:1249-54 ( Co-author)

The Institute for Vaccine Safety Diabetes Workshop Panel. Childhood immunizations and type 1 diabetes: summary of an Institute for Vaccine Safety Workshop. Pediatr Infect Dis J 1999;18:217-22 ( Workshop Panel Member)

Technical Reports :

 

Centers for Disease Control. Surgical sterilization surveillance; Tubal sterilization, 1976-78. Atlanta, Georgia: Centers for Disease Control, 1981 ( Principal Author)

Boyle CA , Decoufle P, Delaney RJ, DeStefano F, et.al. Postservice mortality among Vietnam Veterans. Atlanta, Georgia: Centers for Disease Control, 1987

The Centers for Disease Control Vietnam Experience Study. Health status of Vietnam Veterans: I. Synopsis. Atlanta, Georgia: Centers for Disease Control, 1989 ( Coauthor)

The Centers for Disease Control Vietnam Experience Study. Health status of Vietnam Veterans: III. Medical Examination. Atlanta, Georgia: Centers for Disease Control, 1989 ( Principal Author)

The Centers for Disease Control Vietnam Experience Study. Health status of Vietnam Veterans: IV. Psychological and neuropsychological evaluation. Atlanta, Georgia: Centers for Disease Control, 1989 ( Principal Author)

The Centers for Disease Control Vietnam Experience Study. Health status of Vietnam Veterans: Supplement C. Medical and psychological procedure manuals and forms. Atlanta, Georgia: Centers for Disease Control, 1989 ( Coauthor)

The Centers for Disease Control Veterans Health Study. Comparison of serum levels of 2,3,7,8-tetrachlorodibenzo-p- dioxin with indirect estimates of Agent Orange exposure among Vietnam veterans: Final report. Atlanta, Georgia: Centers for Disease Control, 1989 ( Coauthor)

Centers for Disease Control. Diabetes surveillance, 1980-1987. Atlanta, Georgia: Center for Disease Control, 1990 ( Principal Author)

Centers for Disease Control. Diabetes fact sheets 1990. Atlanta, Georgia: Centers for Disease Control, 1990 ( Coauthor)

Centers for Disease Control and Prevention. Cardiovascular disease surveillance: Ischemic heart disease, 1980-1989. Atlanta, Georgia: Centers for Disease Control and Prevention, 1993 ( Coauthor)

Multiple Sclerosis Council for Clinical Practice Guidelines. Immunizations and Multiple Sclerosis: Evidence-Based Management Strategies for Immunizations in Multiple Sclerosis. Paralyzed Veterans of America, Washington, D.C., November 2001 ( Panel member)

Safety Profile of Pneumococcal Conjugate Vaccines. Report for the World Health Organization Global Advisory Committee on Vaccine Safety, December 2006 ( Principal author)

 
Updated: June 23, 2008