FDA

Enforcement Report

The FDA Enforcement Report is published weekly by the Food and Drug Administration, U.S. Public Health Service, Department of Health and Human Services. It contains information on actions taken in connection with agency regulatory activities.

November 27, 1996

RECALLS AND FIELD CORRECTIONS:  FOODS -- CLASS III ==========
_______________
PRODUCT        Drinking water under the following labels: 
               (a) Crisp 'n Clear Premium Drinking Water, in
               20 ounce, 1 liter and 2 liter plastic bottles;
               (b) Natural Springs Drinking Water, in 1
               gallon, 2-1/2 gallon, and 5 gallon plastic
               containers.  Recall #F-043-7.
CODE           (a) All lots in 20 ounce, 1 liter and 2 liter
               plastic bottles produced in July, August and
               September 1996; (b) All 1 gallon 2-1/2 gallon
               and 5 gallon containers bottled in July,
               August and September 1996.
MANUFACTURER   Marion Pepsi-Cola Bottling Company, Marion,
               Illinois.
RECALLED BY    Manufacturer, by press release on September
               27, 1996, followed by internal bulletins dated
               September 27, 1996, and October 2, 1996, and
               telephone on October 7-12, 1996.  Firm-
               initiated recall complete.
DISTRIBUTION   Missouri, Illinois, Arkansas, Kentucky,
               Tennessee.
QUANTITY       (a) 403,608 20-ounce bottles and 42,945 1-
               liter bottles; (b) 67,789 gallon, 3,505 2-1/2-
               gallon and 980 5-gallon containers were
               distributed.
REASON         Product is adulterated due to the presence of
               coliforms.


RECALLS AND FIELD CORRECTIONS:  DRUGS -- CLASS II ===========
_______________
PRODUCT        Solopak Sodium Chloride Injection USP, 0.9%,
               preservative free, packaged in 2 ml, 3 ml, and
               10 ml pre-filled syringes, used for diluting
               or dissolving compatible parenteral
               medications.  Recall #D-039-7.
CODE           Lot numbers:  96E002B, 96E004B, 96D015B.
MANUFACTURER   SoloPak Medical Products, Franklin Park,
               Illinois.
RECALLED BY    SoloPak Medical Products, Elk Grove Village,
               Illinois, by letter dated October 25, 1996. 
               Firm-initiated recall ongoing.
DISTRIBUTION   Massachusetts, Wisconsin, Tennessee, Texas,
               Illinois, North Carolina, New Jersey, Florida,
               Oklahoma, Louisiana, New York, California,
               Pennsylvania, Michigan.
QUANTITY       47,520 syringes were distributed; firm
               estimated that 48 percent of the syringes
               remained on market at time of recall
               initiation.
REASON         Lack of adequate assurance of sterility.


RECALLS AND FIELD CORRECTIONS:  DRUGS -- CLASS III ==========
_______________
PRODUCT        E-Z-EM brand barium sulfate suspensions, Rx,
               contained in 64 fluid ounce HDPE jugs:
               (a) Liquid Polibar Plus; (b) Liquid E-Z-Paque;
               (c) E-Z-AC.  Recall #D-040/042-7.
CODE           (a) Catalog #L168, Lot numbers: 1B8693A,
               1B8693B, 1B8693C, 1B8694A, 1B8694B, 1B8694C,
               1B8695A, 1B8695B and 1B8695C.  All lots expire
               1/97; (b) Catalog #L186, Lot numbers: 4B8690,
               4B8691, 4B8692 (expire 4/97), 5B9050, 5B9051
               and 5B9052 (expire 5/97); (c) Catalog #L178,
               Lot numbers: 1B8669A, 1B8669B, 1B8669C (expire
               1/97), 2B8670A, 2B8670B, 2B8670C (expire
               2/97), 2B8671A, 2B8671B, and 2B8671C (expire
               2/97). 
MANUFACTURER   Therapex, Division of E-Z-EM Canada Inc.,     
               Providence of Quebec, Canada.

                             -2-RECALLED BY    E-Z-EM, Inc., Westbury, New York
               (distributor), by telephone on October 9,
               1996, followed by letter october 22, 1996. 
               Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide.
QUANTITY       Volume of product in commerce:
               (a)  Liquid Polibar Plus, Catalog #L168
               1B8693A: 140 units
               1B8693B: 149 units
               1B8693C: 98 units
               1B8694A: 146 units 
               1B8694B: 142 units
               1B8694C: 111 units
               1B8695A: 144 units 
               1B8695B: 157 units 
               1B8695C: 109 units 
               (b) Liquid E-Z-Paque, Catalog #L186 
               4B8690: 435 units 
               4B8691: 434 units 
               4B8692: 426 units  
               5B9050: 428 units
               5B9051: 426 units 
               5B9052: 426 units. 
               (c) E-Z-AC, Catalog #L178
               1B8669A: 146 units 
               1B8669B: 146 units 
               1B8669C: 111 units  
               2B8670A: 151 units 
               2B8670B: 140 units 
               2B8670C: 10 units
               2B8671A: 148 units 
               2B8671B: 29 units 
               2B8671C: 60 units.
REASON         Lots fail specifications for total solids and
               assay; lots are also clumping and are
               difficult to resuspend.

_______________
PRODUCT        Phentermine HCl Capsules, USP, 30 mg
               (Blue/Clear), in HDPE bottles of 1,000, Rx
               product indicated in the management of
               exogenous obesity.  Recall #D-043-7.
CODE           Lot No. 6H163 EXP 8/00
               Lot No. 6H164 EXP 8/00
               Lot No. 6H165 EXP 8/00.
MANUFACTURER   Eon Labs Manufacturing, Inc., Laurelton, New
               York.
RECALLED BY    Manufacturer, by letter on October 28, 1996. 
               Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide and Puerto Rico.

                             -3-QUANTITY       The following quantities were distributed per
               lot:
               6H163 - 2,395 bottles
               6H164 - 2,458 bottles
               6H165 - 2,447 bottles.
REASON         Some lots are labeled with incorrect
               expiration -- A four-year expiration period
               was assigned rather than a two-year period.

_______________
PRODUCT        Betuline Lotion, in 2 ounce bottles, topical
               methyl salicylate, OTC drug indicated for
               temporary relief from minor aches and pains. 
               Recall #D-044-7.
CODE           Lot #55-060 EXP 04/97.
MANUFACTURER   Ferndale Laboratories, Inc., Ferndale,
               Michigan.
RECALLED BY    Manufacturer, by letter on September 27, 1996. 
               Firm-initiated recall ongoing.
DISTRIBUTION   Illinois, Indiana, Kansas, Michigan, Missouri,
               New York, North Carolina, Ohio, Pennsylvania.
QUANTITY       17,640 bottles were distributed.
REASON         Potency is not assured through expiration date
               -- One stability lot is subpotent for methyl
               Salicylate.

_______________
PRODUCT        Dermaline Skin-Bleaching Cream, packed in 1
               ounce, 2 ounce and 4 ounce plastic jars, a
               non-prescription skin cream.  Recall #D-045-7.
CODE           IND #13505.
MANUFACTURER   Leivon Cosmetics, Inc., Santo Domingo,
               Dominican Republic.
RECALLED BY    Castillo Distributor, Inc., Little Ferry, New
               Jersey, by letter on October 29, 1996.  Firm-
               initiated recall ongoing.
DISTRIBUTION   New York, New Jersey.
QUANTITY       Approximately 8 cases (144 8-ounce jars per
               case); 7 cases (144 2-ounce jars per case);
               719 cases (48 4-ounce jars per case) were
               distributed; firm estimated that little or no
               product remained on market at time of recall
               initiation.
REASON         FDA analysis found that product does not
               contain labeled active ingredient,
               hydroquinone.  


RECALLS AND FIELD CORRECTIONS:  BIOLOGICS -- CLASS II =======
_______________
PRODUCT        (a) Whole Blood; (b) Red Blood Cells; (c)
               Platelets; (d) Fresh Frozen Plasma; (e)
               Recovered Plasma.  Recall #B-485/489-6.
                             -4-CODE           Unit numbers:  (a) 6005664; (b) 1335802,
               1837281, 7710774, 1446158, 8125231;         
               (c) 1335802, 1837281, 7710774, 1446158,
               8125231; (d) 1335802, 7710774, 8125231; (e)
               1837281, 1446158.
MANUFACTURER   LifeSource Blood Services, Glenview, Illinois.
RECALLED BY    Manufacturer, by letters dated December 18,
               19, 20, 1995.  Firm-initiated recall complete.
DISTRIBUTION   Illinois.
QUANTITY       (a) 1 unit; (b) 5 units; (c) 5 units; (d) 3
               units; (e) 2 units. 
REASON         Blood product, which tested initially reactive
               for HIV-1, EIA repeat negative and Western
               Blot indeterminate; donor was subsequently not
               deferred and products were distributed.

_______________
PRODUCT        (a) Whole Blood; (b) Red Blood Cells; (c)
               Platelets; (d) Fresh Frozen Plasma; (e)
               Cryoprecipitate AHF; (f) Source Leukocytes;
               (g) Platelets, further manufacturing; (h)
               Recovered Plasma.  Recall #B-523/530-6.
CODE           Unit numbers:  31T26238, 31T28580, 31T34357,
               31T39341, 31T45097, 31T46677, 31T50570,
               31T55355, 31T57431, 31T59725, 31T63742,
               31T68772, 31T71919, 31T74551, 31T76570,
               31T82531, 31T88406, 31T92445, 31T94597,
               31T97707, 31N40940, 31T05137, 31V20471,
               31T15917, 31T18879, 31T20853. 
MANUFACTURER   American Red Cross, Buffalo, New York.
RECALLED BY    American Red Cross, Rochester, New York;
               (American Red Cross National Headquarters,
               Rosslyn, Virginia (Recovered Plasma), by
               letter on various dates in February 1996. 
               Firm-initiated recall complete.
DISTRIBUTION   New York, Pennsylvania, California, Georgia,
               Maryland, Missouri, South Carolina, Tennessee,
               Switzerland.
QUANTITY       (a) 1 unit; (b) 25 units; (c) 19 units; (d) 8
               units; (e) 7 units; (f) 1 unit; (g) 2 units;
               (h) 17 units were distributed.
REASON         Blood products, which tested non-reactive to
               anti-HIV-1, but collected from a donor who
               initially tested IR for anti-HIV-1, no repeat
               anti-HIV testing was performed; donor was
               subsequently allowed to be reentered
               improperly, and products were distributed.

_______________
PRODUCT        (a) Whole Blood; (b) Red Blood Cells; (c) Red
               Blood Cells, Deglycerolized; (d) Platelets;
               (e) Platelets, Pheresis; (f) Fresh Frozen

                             -5-               Plasma; (g) Single Donor Plasma Liquid; (h)
               Cryoprecipitated AHF; (i) Recovered Plasma. 
               Recall #B-534/542-6.
CODE           Contact FDA, Center for Biologics Evaluation
               and Research, Office of Compliance (301) 594-
               1191 for individual unit numbers recalled.
MANUFACTURER   The American National Red Cross, Arlington,
               Virginia.
RECALLED BY    Manufacturer, by letters from 1988 through
               1995.  Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide and international.
QUANTITY       Approximately 11,286 units of various blood
               products were distributed.
REASON         Blood products tested negative for the
               antibody to the human immunodeficiency virus
               type 1 (anti-HIV-1) and the hepatitis B
               surface antigen (HBsAg) but were collected
               from donors who previously tested repeatedly
               reactive for anti-HIV-1 or HBsAg and had
               confirmatory testing inappropriately repeated
               or indeterminate Western blots incorrectly
               interpreted as negative. 

_______________
PRODUCT        (a) Red Blood Cells; (b) Recovered Plasma. 
               Recall B-545/546-6.
CODE           Unit #40GN10981.
MANUFACTURER   American Red Cross, Peoria, Illinois.
RECALLED BY    Manufacturer, by letter dated February 5,
               1996.  Firm-initiated recall complete.
DISTRIBUTION   New York.
QUANTITY       1 unit of each component.
REASON         Blood products tested initially reactive for
               HBsAg and then tested into compliance.

_______________
PRODUCT        (a) Red Blood Cells; (b) Platelets; (c)
               Recovered Plasma.  Recall #B-640/642-6.
CODE           Unit #38F01212.
MANUFACTURER   American Red Cross, Fort Wayne, Indiana.
RECALLED BY    Manufacturer, by telephone on or about January
               23, 1995.  Firm-initiated recall complete.
DISTRIBUTION   Indiana.
QUANTITY       1 unit of each component were distributed.
REASON         Blood products were collected from a donor who
               tested repeat reactive for HBsAg.

_______________
PRODUCT        Recovered Plasma.  Recall #B-664-6.
CODE           Unit numbers:  06GE14760, 06LR82215,
               06FR20153, 06GE17351, 06LR80684, 06LV75749,
               06LT56872, 06GE14791, 06LP42293, 06FK51763,
               06GK12084, 06LS82447.
                             -6-MANUFACTURER   American Red Cross, Los Angeles.
RECALLED BY    Manufacturer, by letters dated August 12 and
               30, 1993, and November 24, 1993.  Firm-
               initiated recall complete.
DISTRIBUTION   New Jersey, New York, The Netherlands.
QUANTITY       12 units were distributed. 
REASON         Blood products tested repeat reactive for HIV.

_______________
PRODUCT        Red Blood Cells.  Recall #B-706-6.
CODE           Unit numbers:  X34424, L24375, L46697.
MANUFACTURER   Blood Bank of San Bernardino and Riverside
               Counties, San Bernardino, California.
RECALLED BY    Manufacturer, by letter dated July 26, 1993. 
               Firm-initiated recall complete.
DISTRIBUTION   California.
QUANTITY       3 units were distributed. 
REASON         Blood products tested negative for all
               infectious diseases were collected from a
               donor who previously tested IR for anti-HIV-1,
               and was never properly reentered. 

_______________
PRODUCT        (a) Albuminar-25; (b) Albuminar-20; (c)
               Albuminar-5; (d) Monoclate-P; (e) Plasma Plex. 
               Recall #B-026/030-7.
CODE           (a-c & e) All in-date lots; (d) Lot #P72304.
MANUFACTURER   Centeon L.L.C., Kankakee, Illinois.
RECALLED BY    Centeon L.L.C., A company of Armour and
               Behring.  King of Prussia, Pennsylvania, by
               telephone on September 20, 1996, and by
               letters on September 23 and 24, 1996, and
               October 4, 1996.  Firm-initiated recall
               ongoing.  See also FDA talk paper T96-67,
               October 4, 1996. 
DISTRIBUTION   Nationwide and international.
QUANTITY       18,508 - 50 ml vials and 1,677 - 500 ml vials
               of 5%, and 70,922 - 50 ml vials and 52,135 -
               100 ml vials of 25% Albuminar in the dropped
               lot category were distributed.  The firm
               estimates that 30% of the vials remain on the
               market; 1,595 vials of Monoclate-P were
               distributed, with the firm estimating that 250
               vials remain on the market.
               The amount of Albuminar and Plasma Plex
               distributed is not available at this time. 
               The firm estimates that 30% of the distributed
               product remains on the market.
REASON         Biological products that are sensitive to
               environmental contamination may not have been
               processed according to current Good
               Manufacturing Practices. 

                             -7-_______________ 
PRODUCT        Red Blood Cells.  Recall #B-066-7.
CODE           Unit #0657919.
MANUFACTURER   Coffee Memorial Blood Center, Inc., Amarillo,
               Texas.
RECALLED BY    Manufacturer, by telephone on February 6,
               1996, followed by letters dated February 8 and
               9, 1996.  Firm-initiated recall complete.
DISTRIBUTION   Texas.
QUANTITY       1 unit was distributed.
REASON         Blood product was collected from a donor who
               immigrated from a malarial endemic area.

_______________
PRODUCT        Platelets.  Recall #B-078-7.
CODE           Unit numbers:  36P20707 and 36P26113. 
MANUFACTURER   American Red Cross, Columbia, South Carolina.
RECALLED BY    Manufacturer, by telephone and by letter dated
               May 10, 1995.  Firm-initiated recall complete.
DISTRIBUTION   Georgia and South Carolina.
QUANTITY       2 units were distributed.
REASON         Blood products were collected from a donor
               exposed to hepatitis.

_______________
PRODUCT        Platelets, pheresis.  Recall #B-085-7.
CODE           Unit #36Q43009.
MANUFACTURER   American Red Cross Blood Services, Columbia,
               South Carolina.
RECALLED BY    Manufacturer, by telephone on November 24,
               1995.  Firm-initiated recall complete.
DISTRIBUTION   South Carolina.
QUANTITY       1 unit was distributed.
REASON         Blood product was collected from a donor who
               was taking the drug Proscar at the time of
               donation.

_______________
PRODUCT        (a) Red Blood Cells; (b) Fresh Frozen Plasma. 
               Recall #B-086/087-7.
CODE           Unit numbers:  (a) 1222126, 1222133, 1222138,
               1706175, 3127667, 3127668, 4109854; (b)
               1706175.
MANUFACTURER   Carter Blood Center, Fort Worth, Texas.
RECALLED BY    Manufacturer, by telephone on May 8, 1996. 
               Firm-initiated recall complete.
DISTRIBUTION   Texas.
QUANTITY       (a) 7 units; (b) 1 unit.
REASON         Blood products corresponded to a unit of
               Pooled Platelets which was positive for
               Staphylococcus aureus. 

                             -8-_______________
PRODUCT        (a) Red Blood Cells; (b) Fresh Frozen Plasma. 
               Recall #B-090/091-7.
CODE           Unit #23031-8103.
MANUFACTURER   United Blood Services, Billings, Montana.
RECALLED BY    Manufacturer, by letter August 3, 1994.  Firm-
               initiated recall complete.
DISTRIBUTION   Montana.
QUANTITY       1 unit was distributed.
REASON         Blood products were collected from a donor
               whose health history screening was
               inadequately performed.

_______________
PRODUCT        Platelets.  Recall #B-092-7.
CODE           Unit #L25247.
MANUFACTURER   H.C.S.C. Blood Center, Bethlehem,
               Pennsylvania.
RECALLED BY    Manufacturer, by telephone on August 27, 1996. 
               Firm-initiated recall complete.
DISTRIBUTION   Pennsylvania.
QUANTITY       1 unit.
REASON         Blood product was collected from a donor whose
               health history screening was inadequately
               performed.

_______________
PRODUCT        (a) Red Blood Cells; (b) Recovered Plasma. 
               Recall #B-093/094-7.
CODE           Unit #23130-6011.
MANUFACTURER   United Blood Services, Billings, Montana.
RECALLED BY    Manufacturer, by letter dated May 18, 1995. 
               Firm-initiated recall complete.
DISTRIBUTION   Texas.
QUANTITY       1 unit was distributed.
REASON         Blood products were collected from a donor who
               reported a history of body piercing two months
               prior to donation.

_______________
PRODUCT        (a) Red Blood Cells; (b) Platelets; (c) Fresh
               Frozen Plasma; (d) Cryoprecipitated AHF; (e)
               Recovered Plasma.  Recall #B-095/099-7.
CODE           Unit numbers:  (a) 30G86549, 30Y37362,
               30X40720, 30X54667, 30H88208, 30J82030,
               30Y66071, 30Y66790, 30Y72047, 30FX32492; (b)
               30X54667, 30FX32492; (c) 30X54667, 30J82030,
               (d) 30Y66790; (e) 30G86549, 30Y37362,
               30X40720, 30H88208, 30Y66071, 30Y66790,
               30FX32492;
MANUFACTURER   American Red Cross Blood Services; Ashley,
               Pennsylvania.

                             -9-RECALLED BY    Manufacturer, by letter dated December 6,
               1995.  Firm-initiated recall complete.
DISTRIBUTION   Pennsylvania.
QUANTITY       (a) 10 units; (b) 2 units; (c) 2 units; (d) 1
               unit; (e) 7 units were distributed.
REASON         Blood products tested negative for the
               antibody to the human immunodeficiency virus
               type 1 (anti-HIV-1) were collected from a
               donor who previously tested repeatedly
               reactive for anti-HIV-1.

_______________
PRODUCT        (a) Red Blood Cells; (b) Platelets; (c)
               Cryoprecipitated AHF; (d) Recovered Plasma. 
               Recall #B-100/103-7.
CODE           Unit numbers:  30F61116, 30F62204.
MANUFACTURER   American Red Cross Blood Services, Ashley,
               Pennsylvania.
RECALLED BY    Manufacturer, by letters dated December 27 and
               29, 1995.  Firm-initiated recall complete.
DISTRIBUTION   Pennsylvania and New York.
QUANTITY       2 units of each component were distributed.
REASON         Blood products tested negative for antibody to
               the human immunodeficiency virus type 1 (anti-
               HIV-1), but were collected from a donor who
               previously tested repeatedly reactive for
               anti-HIV-1.

_______________
PRODUCT        (a) Red Blood Cells; (b) Recovered Plasma. 
               Recall #B-104/105-7.
CODE           Unit numbers:  21GM44257 and 21GM46348.
MANUFACTURER   American Red Cross Blood Services, Portland,
               Oregon.
RECALLED BY    Manufacturer, by letters of February 16 and
               21, 1996.  Firm-initiated recall complete.
DISTRIBUTION   California, Washington state.
QUANTITY       2 units of each component were distributed.
REASON         Blood products were collected from a donor who
               was taking the drug Proscar.

_______________
PRODUCT        Platelets.  Recall #B-107-7.
CODE           Unit numbers:   J07085  J07086  J07088  J07090
               J07091  J07092  J07094  J07095  J07096  J07101 
               J07102  J07103.  
MANUFACTURER   H.C.S.C. Blood Center, t/a Miller Memorial
               Blood Center, Bethlehem, Pennsylvania.
RECALLED BY    Manufacturer, by letters dated April 3, 1996,
               and June 24, 1996.  Firm-initiated recall
               complete.
DISTRIBUTION   Pennsylvania.
QUANTITY       12 units were distributed.
                            -10-REASON         Blood products were stored below specified
               temperature range.


RECALLS AND FIELD CORRECTIONS:  BIOLOGICS -- CLASS III ======
_______________
PRODUCT        (a) Red Blood Cells; (b) Recovered Plasma. 
               Recall #B-547/548-6.
CODE           Unit  #40GN11000.
MANUFACTURER   American Red Cross, Peoria, Illinois.
RECALLED BY    Manufacturer, by letter dated February 5,
               1996.  Firm-initiated recall complete.
DISTRIBUTION   Illinois.
QUANTITY       1 unit of each component was distributed.
REASON         Blood products tested initially reactive for
               HBsAg and then tested into compliance.

_______________
PRODUCT        (a) Red Blood Cells; (b) Recovered Plasma. 
               Recall B-584/585-6.
CODE           Unit #40GV34620.
MANUFACTURER   American Red Cross Blood Services, Peoria,
               Illinois.
RECALLED BY    Manufacturer, by letter dated April 19, 1996. 
               Firm-initiated recall complete.
DISTRIBUTION   Illinois and California.
QUANTITY       1 unit of each component.
REASON         Blood products, which tested repeatedly
               reactive for the hepatitis B surface antigen
               (HBsAg), and then were subjected to additional
               retesting, were distributed.

_______________
PRODUCT        (a) Platelets, Pheresis; (b) Source Plasma. 
               Recall #B-587/588-6.
CODE           Unit numbers:  (a) 40Z02027, 40Z02064; (b)
               40P03137.
MANUFACTURER   American Red Cross Blood Services, Peoria,
               Illinois.
RECALLED BY    Manufacturer, by letter dated February 27,
               1996.  Firm-initiated recall complete.
DISTRIBUTION   Illinois.
QUANTITY       (a) 2 units; (b) 1 unit was distributed.
REASON         Blood products which tested repeatedly
               reactive for HBsAg, were subjected to
               additional retesting, or tested negative for
               HBsAg, were collected from a donor who
               previously tested repeatedly reactive for
               HBsAg.

_______________
PRODUCT        Recovered Plasma.  Recall #B-589-6.
CODE           Unit #40GR43986.
                            -11-MANUFACTURER   American Red Cross Blood Services, Peoria,
               Illinois.
RECALLED BY    Manufacturer, by questionable plasma inquiry
               dated April 10, 1996.  Firm-initiated recall
               complete.
DISTRIBUTION   California.
QUANTITY       1 unit was distributed.
REASON         Blood product tested repeatedly reactive for
               the hepatitis B surface antigen (HBsAg) and
               was subjected to additional retesting.

_______________
PRODUCT        Platelets, Pheresis.  Recall #B-675-6.
CODE           Unit numbers 07M24460 and 07M24461.
MANUFACTURER   American Red Cross, Tucson, Arizona.
RECALLED BY    Manufacturer, by letter dated April 23, 1993. 
               Firm-initiated recall complete.
DISTRIBUTION   Arizona.
QUANTITY       2 units were distributed.
REASON         Blood products were incorrectly tested for
               HBsAg.

_______________
PRODUCT        Platelets.  Recall #B-075-7.
CODE           Unit #53T33841.
MANUFACTURER   American Red Cross, Baltimore, Maryland.
RECALLED BY    Manufacturer, by telephone on or about
               February 9, 1996, followed by letter on
               February 14, 1996.  Firm-initiated recall
               complete.
DISTRIBUTION   Virginia.
QUANTITY       1 unit was distributed. 
REASON         Blood product had an incorrect ratio of blood
               to anticoagulant. 

_______________
PRODUCT        Red Blood Cells.  Recall #B-076-7.
CODE           Unit numbers 53FH53336, 53FH53350.
MANUFACTURER   American Red Cross, Baltimore, Maryland.
RECALLED BY    Manufacturer, by telephone on March 4, 1996,
               and by letter dated March 18, 1996.  Firm-
               initiated recall complete.
DISTRIBUTION   Maryland.
QUANTITY       2 units were distributed.
REASON         Blood products were collected from donors
               whose hematocrit was not determined in donor
               suitability.

_______________
PRODUCT        Red Blood Cells.  Recall #B-077-7.
CODE           Unit numbers:  17178-8186, 17178-8187.
MANUFACTURER   United Blood Services, McAllen, Texas.

                            -12-RECALLED BY    Blood Services, Inc., Scottsdale, Arizona, by
               letter on April 16, 1996.  Firm-initiated
               recall complete.
DISTRIBUTION   Texas.
QUANTITY       2 units were distributed.
REASON         Red blood cells remained at room temperature
               for an unknown amount of time.

_______________
PRODUCT        Red Blood Cells.  Recall #B-083-7.
CODE           Unit #017FH34709 (split unit).
MANUFACTURER   American Red Cross, St. Paul, Minnesota.
RECALLED BY    Manufacturer, by telephone on November 8,
               1995.  Firm-initiated recall complete.
DISTRIBUTION   Minnesota.
QUANTITY       1 unit was distributed.
REASON         Blood product was incorrectly tested for
               syphilis.

_______________
PRODUCT        Red Blood Cells.  Recall #B-084-7.
CODE           Unit #0347266.
MANUFACTURER   Blood Bank of Delaware, Inc., Newark,
               Delaware.
RECALLED BY    Manufacturer, by telephone on April 6, 1995. 
               Firm-initiated recall complete.
DISTRIBUTION   Delaware.
QUANTITY       1 unit was distributed.
REASON         Blood product was labeled with an extended
               expiration date.

_______________
PRODUCT        Platelets.  Recall #B-106-7.
CODE           Unit numbers:  0333461, 0353701, 0353703,
               0353705, 0353706
MANUFACTURER   Blood Bank of Delaware, Inc., Newark,
               Delaware.
RECALLED BY    Manufacturer, by telephone on June 10, 1995. 
Firm-initiated recall complete.
DISTRIBUTION   Delaware.
QUANTITY       5 units were distributed.
REASON         Blood products were not stored under
               continuous agitation.


RECALLS AND FIELD CORRECTIONS:  DEVICES -- CLASS II =========
_______________
PRODUCT        Ti-Fit (Titanium Stem) Total Hip System,
               Femoral Stem, Implantable Orthopedic Devices,
               which have not been implanted, under the
               following Product Numbers and Lot Numbers:
               Domestic Catalogue Numbers/Description

                            -13-               (a) 12-4301/Size 1 Stem, 115 mm Length, 
                   Collared
               12-4302/Size 2 Stem, 120 mm Length, Collared
               12-4303/Size 3 Stem, 130 mm Length, Collared
               12-4304/Size 4 Stem, 140 mm Length, Collared
               12-4305/Size 5 Stem, 145 mm Length, Collared
               12-4306/Size 6 Stem, 150 mm Length, Collared
               12-4307/Size 7 Stem, 155 mm Length, Collared
               12-4308/Size 8 Stem, 160 mm Length, Collared
               12-4309/Size 9 Stem, 170 mm Length, Collared
               916470/Size 2 Stem, 170 mm Length, Collared
               916507/Size 1 Stem, 165 mm Length, Collared
               (b) 12-4331/Size 1 Stem, 115 mm Length,
                   Collarless 
               12-4332/Size 2 Stem, 120 mm Length, Collarless
               12-4333/Size 3 Stem, 130 mm Length, Collarless
               12-4334/Size 4 Stem, 140 mm Length, Collarless
               12-4335/Size 5 Stem, 145 mm Length, Collarless
               12-4336/Size 6 Stem, 150 mm Length, Collarless
               12-4337/Size 7 Stem, 155 mm Length, Collarless
               12-4338/Size 8 Stem, 160 mm Length, Collarless
               12-4339/Size 9 Stem, 170 mm Length, Collarless
               Foreign Catalog Numbers/Description
               (c) 52-4301/Size 1 Stem, 115 mm Length,
                   Collared
               52-4302/Size 2 Stem, 120 mm Length, Collared
               52-4303/Size 3 Stem, 130 mm Length, Collared
               52-4304/Size 4 Stem, 140 mm Length, Collared
               52-4305/Size 5 Stem, 145 mm Length, Collared
               52-4306/Size 6 Stem, 150 mm Length, Collared
               52-4307/Size 7 Stem, 155 mm Length, Collared
               52-4308/Size 8 Stem, 160 mm Length, Collared
               52-4309/Size 9 Stem, 170 mm Length, Collared
               (d) 52-4331/Size 1 Stem, 115 mm Length,
                   Collarless
               52-4332/Size 2 Stem, 120 mm Length, Collarless
               52-4333/Size 3 Stem, 130 mm Length, Collarless
               52-4334/Size 4 Stem, 140 mm Length, Collarless
               52-4335/Size 5 Stem, 145 mm Length, Collarless
               52-4336/Size 6 Stem, 150 mm Length, Collarless
               52-4337/Size 7 Stem, 155 mm Length, Collarless
               52-4338/Size 8 Stem, 160 mm Length, Collarless
               52-4339/Size 9 Stem, 170 mm Length, Collarless
               (e) 71971403/Custom made product
               71971404/Custom made product
               71971405/Custom made product
               71971406/Custom made product
               71971407/Custom made product
               914334/Custom made product.  
               Recall #Z-135/139-7.
CODES          The following lots, all of which were
               manufactured prior to October 1994 and shipped
               to domestic accounts, are subject to recall:
                            -14-               Seven (7) digit Lot Numbers beginning with the
               following:
               1U; 2U; 3U; 4U; 1W; 2W; 3W; 4W; 1X; 2X; 3X;
               4X; 1Y; 2Y; 3Y; 4Y; 1Z; 2Z; 3Z; 4Z; 1A; 2A;
               3A; 4A; 1B; 2B; 3B; 4B; 1C; 2C; 3C; 4C; 1D;
               and 2D.
               Ten (10) digit Lot Numbers beginning with the
               following:
               405; 406; 407; 408; and 409
               The following lots, all of which were shipped
               to foreign accounts, are subject to recall:
               1.  All lot numbers beginning with the letter
               "T" that have only eight (8) digits,
               indicating production  before 1989; and,
               2.  All lot numbers beginning with the letter
               "T", which have nine (9) or ten (10) digits
               and where the sixth digit (which indicates the
               year) is smaller than "5"; and,
               3.  Lots with the sixth digit as a "5" and
               beginning with the following digits: 
               T00465, T00475, T00495, T00505, T00545,
               T00745, T01145, T01165, T01245, T02215,
               T03665, T03675, T03895, T04795, T04835,
               T04845, T04855, T04865, T05725, T05735,
               T07875, and T07885 and,
               4.  Lots with the sixth digit as a "6" and
               beginning with the following digits:
               T00226, T00236, T00246, T00256, T00266,
               T00276, T00286, T00296, T00306, T00316,
               T00336, T00346, T00356, T00366, T00376,
               T00386, T00396, T01436, T01466, T01496,
               T01506, T01516, T03326, T03356, T03436,
               T03476, T03976, T06396, and T06406.
MANUFACTURER   Smith & Nephew Richards, Inc., Smith & Nephew
               Orthopedics, Memphis, Tennessee. 
RECALLED BY    Manufacturer, by letter on September 26, 1996. 
               Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide and international.
QUANTITY       4,200 systems were distributed.
REASON         Laser etching may cause the femoral stems to
               fracture in use, requiring revision surgery to
               replace the broken hip implant.


RECALLS AND FIELD CORRECTIONS:  DEVICES -- CLASS III ========
_______________
PRODUCT        Vitros 250 and 950 Reference Fluids, used as a
               reference fluid for potentiometric assays on
               the Vitros (formerly Ektachem) 950 Chemistry
               System and Vitros (formerly Ektachem) 250
               Analyzer:  (a) Vitros 250, Catalog #176 5304; 
               (b) Vitros 950, Catalog #805 7812.
               Recall #Z-143/144-7.
                            -15-CODE           Lot numbers:  (a) M2057; (b) K1423, M1460,
               P1492.
MANUFACTURER   Johnson & Johnson Clinical Diagnostics,
               Rochester, New York.
RECALLED BY    Johnson & Johnson Clinical Diagnostics,
               Rochester, New York, by letter dated September
               30, 1996.  Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide and international.
QUANTITY       (a) 1,952 boxes (30 units per box); (b) 3,833
               boxes (30 units per box) were distributed.
REASON         A portion of these lots had a diluted
               electrolyte concentration that could result in
               a shift in the sodium and chloride results.


RECALLS AND FIELD CORRECTIONS:  VETERINARY PRODUCTS -- CLASS III ========
_______________
PRODUCT        Tribrissen 480 Tablets, in 100 and 200 tablet
               bottles, Rx veterinary synthetic
               antibacterial.  Recall #V-019-7.
CODE           Lot numbers:  002972, 003092, 003181.
MANUFACTURER   Mallinckrodt Veterinary, Inc., Bray, Ireland.
RECALLED BY    Mallinckrodt Veterinary, Inc., Mundelein,
               Illinois, by letter dated September 3, 1996. 
               Firm-initiated recall ongoing.
DISTRIBUTION   Nationwide.
QUANTITY       702 bottles were distributed.
REASON         The bottle labels for both sizes contained a
               typographical error.  Trimethoprim was listed
               at 80g strength instead of 80 mg strength.

_______________
PRODUCT        TM-50 (oxytetracycline) Type A Medicated
               Article, in 50 pound bags.  Recall #V-020-7.
CODE           Lot numbers FPX9X25 and FP10X25.
MANUFACTURER   Farmland Industries, Inc., Eagle Grove, Iowa.
RECALLED BY    Farmland Industries, Inc., Kansas City,
               Missouri, by telephone on August 9, 12-13,
               1996, followed by letter on September 16,
               1996.  Firm-initiated recall complete.
DISTRIBUTION   Nebraska.
QUANTITY       160 bags were distributed.
REASON         Product failed 12 month stability testing.

                            -16-

END OF ENFORCEMENT REPORT FOR NOVEMBER 27, 1996.  BLANK PAGES MAY FOLLOW.

                                   ####

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