Tobacco Products

Research Priorities

To inform the regulatory activities defined by the Tobacco Control Act, CTP has identified research areas that will expand the science base related to tobacco and health, including:

A scientist looking into a tube

  1. understanding the diversity of tobacco products
  2. reducing addiction to tobacco products
  3. reducing toxicity and carcinogenicity of tobacco products and smoke
  4. understanding the adverse health consequences of tobacco use
  5. understanding communications about tobacco products
  6. understanding tobacco product marketing
  7. understanding how economics and policies affect tobacco product use

Although a vast and sound science base exists in many of these areas, new research supported by CTP will provide additional scientific evidence for regulatory decision making and for assessing regulatory outcomes. Current research priorities include:

  1. Nicotine dependence threshold in youth and adults, and impact of nicotine reduction on tobacco product use behavior (e.g., topography, switching, multiple use, initiation, cessation, relapse)
  2. Cigar (small, large, cigarillos) initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence, and toxicity
  3. Smokeless tobacco initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence, and toxicity
  4. E-cigarette initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence, and toxicity
  5. Other tobacco product (e.g., hookah, pipes, dissolvables) initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence, and toxicity
  6. Impact of tobacco product characteristics, (e.g., ingredients, constituents, components, additives [such as flavors], labeling, marketing) on initiation, especially by youth and other vulnerable populations*
  7. Toxicity thresholds for each of the 20 harmful and potentially harmful constituents identified in the March 2012 Draft Guidance for Industry
  8. Statistical modeling of the public health impact of FDA/CTP regulation of potential modified-risk tobacco products (e.g., product standards, communications regarding risks of tobacco products)
  9. Consumer perceptions of tobacco products, including the impact of labeling and marketing
  10. Effective communication strategies regarding harmful and potentially harmful constituents and risks of tobacco products

*The vulnerable populations and subgroups referenced include:

  • age
  • gender
  • race
  • ethnicity
  • income
  • occupation
  • geographic location
  • people with mental health or medical co-morbidities
  • military/veterans
  • the LBGTQ community
  • pregnant women/women of reproductive age

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Page Last Updated: 04/03/2015
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