This guidance provides information in response to frequently asked questions that the Center for Tobacco Products (CTP) may receive from retailers and other interested stakeholders regarding the issuance of civil money penalties and no-tobacco-sale orders for violations of Federal Food, Drug, and Cosmetic Act (FD&C Act) (21 U.S.C. 301 et seq.) requirements relating to tobacco products in retail outlets. In particular, the guidance provides information about CTP’s enforcement of the requirement that tobacco products may not be sold or distributed in violation of FDA’s regulations restricting the sale and distribution of cigarettes and smokeless tobacco to protect children and adolescents (21 CFR part 1140) and about procedures the Agency follows when it initiates enforcement actions. Additional information on civil money penalties and no-tobacco-sale orders can be found in FDA’s guidance for FDA and tobacco retailers Civil Money Penalties and No-Tobacco-Sale Orders for Tobacco Retailers (CMP and NTSO guidance).