• Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services


  • Print
  • Share
  • E-mail

NuvaRing (etonogestrel/ethinyl estradiol vaginal ring)

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER)


October 2014

Summary View


“What should I do if my NuvaRing comes out of my vagina?”

  • added...Reinsert the ring as soon as you remember...do not reinsert the NuvaRing that has been out of your vagina...Use another birth control method, such as male condoms with spermicide, until the new NuvaRing has been used for 7 days in a row.


June 2014

Summary View


Postmarketing Experience
  • Reproductive system and breast disorders: galactorrhea 


October 2013

Summary View


Thromboembolic Disorders and Other Vascular Problems
  • Stop NuvaRing use if an arterial thrombotic or venous thromboembolic event (VTE) occurs. Stop NuvaRing use if there is unexplained loss of vision, proptosis, diplopia, papilledema, or retinal vascular lesions. Evaluate for retinal vein thrombosis immediately. [See Adverse Reactions (6).]
  • If feasible, stop NuvaRing at least four weeks before and through two weeks after major surgery or other surgeries known to have an elevated risk of thromboembolism, and during and following prolonged immobilization.