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U.S. Department of Health and Human Services


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Peridex (chlorhexidine gluconate) Oral Rinse, 0.12 percent

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER)


January 2013

Summary View


  • ..... Anaphylaxis, as well as serious allergic reactions, have been reported during  postmarketing use with dental products containing chlorhexidine. (SEE  CONTRAINDICATIONS).


What to expect when using Peridex Chlorhexidine Gluconate 0.12% Oral Rinse

  • If you develop allergic symptoms such as skin rash, itch, generalized swelling, breathing difficulties, light headedness, rapid heart rate, upset stomach or diarrhea, seek medical attention immediately. Peridex oral rinse should not be used by persons who have a sensitivity to it or its components.