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U.S. Department of Health and Human Services


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Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – June 2011

Summary View


Corgard (nadolol) tablets


Corzide (nadolol and bendroflumethiazide) tablets



Major Surgery
  • Chronically administered beta-blocking therapy should not be routinely withdrawn prior to major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.