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U.S. Department of Health and Human Services

Safety

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Inderal (propranolol HCL) tablets and Inderal LA (propranolol hydrochloride) long acting capsules

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – March 2011

 

Summary View

 

WARNINGS

Major Surgery
  • Chronically administered beta-blocking therapy should not be routinely withdrawn prior to major surgery, however the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.