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U.S. Department of Health and Human Services

Safety

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Betapace (sotalol hydrochloride) and Betapace AF (sotalol hydrochloride)

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – February 2011

Summary View

 

PRECAUTIONS

Drug Interactions
  • Digoxin: ...Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can increase the risk of bradycardia.