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U.S. Department of Health and Human Services

Safety

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Catapres (clonidine) tablets and Catapres-TTS (clonidine) transdermal therapeutic system

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – April 2010

 

Summary View

 

PRECAUTIONS 

Drug Interactions
  • Monitor heart rate in patients receiving clonidine concomitantly with agents known to affect sinus node function of AV nodal conduction, e.g., digitalis, calcium channel blockers, and beta-blockers. Sinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concomitantly with diltiazem or verapamil.
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