Safety

Cardura XL (doxazosin mesylate) extended release tablets

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER)  

June 2015

Summary View

WARNINGS AND PRECAUTIONS

  • Priapism Rarely (probably less frequently than once in every several thousand patients), alpha-1 antagonists, including doxazosin, have been associated with priapism (painful penile erection, sustained for hours and unrelieved by sexual intercourse or masturbation). Because this condition can lead to permanent impotence if not promptly treated, patients must be advised about the seriousness of the condition.

ADVERSE REACTIONS 

  • …gastrointestinal obstruction…

 

March 2010

Summary View

PRECAUTIONS

Drug Interactions
  • Concomitant administration of CARDURA XL with a phosphodiesterase-5 (PDE-5) inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension.

 

Page Last Updated: 07/14/2015
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