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U.S. Department of Health and Human Services


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Parnate (tranylcypromine sulfate) tablets

Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – May 2010 and November 2009


May 2010 Summary View



In combination with sympathomimetics
  • Parnate should not be administered in combination with sympathomimetics, including amphetamines which may be found in many herbal preparations
  • Cerebral hemorrhage may also occur



November 2009 Summary View



  • Parnate is contraindicated: In combination with selective norepinephrine reuptake inhibitors (SNRIs)