Tramadol hydrochloride tablets
- Ultracet (tramadol HCl/acetaminophen) tablets
- Ultram (tramadol hydrochloride) tablets
Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) -- September 2009
Serotonin Syndrome Risk
- The development of a potentially life-threatening serotonin syndrome may occur with the use of tramadol products...
Information for Patients
- Patients should be informed that tramadol may cause seizures and/or serotonin syndrome with concomitant use of serotonergic agents (including SSRIs, SNRIs, and triptans) or drugs that significantly reduce the metabolic clearance of tramadol.