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U.S. Department of Health and Human Services

Safety

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Bovine Spongiform Encephalopathy (BSE) Information

The U.S. Food and Drug Administration (FDA) learned earlier this year that some vaccines were manufactured with bovine-derived materials obtained from countries in which bovine spongiform encephalopathy (BSE) or a substantial risk for BSE exists. A "Notice to Readers: Public Health Service Recommendations for the Use of Vaccines Manufactured with Bovine-Derived Materials" was published in the MMWR December 22, 2000 [vol. 49(50);1137-8]. See the CBER information page on BSE