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U.S. Department of Health and Human Services

Safety

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Serentil (mesoridazine besylate)

Important labeling changes for all dosage forms of Serentil including a boxed WARNING to advise clinicians that Serentil has been shown to prolong the QTc interval in a dose related manner and drugs with this potential have been associated with torsade de pointes-type arrhythmias and sudden death.

[September 22, 2000 - Letter - Novartis]