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U.S. Department of Health and Human Services

Safety

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Transfusion Related Acute Lung Injury (TRALI)

Audience: Health Professionals, particularly Respiratory Specialists

FDA alerts health professionals to the risk of Transfusion Related Acute Lung Injury (TRALI) in patients who receive blood products, particularly plasma-containing products. TRALI is a serious pulmonary syndrome that can lead to death if not recognized and treated appropriately. Recognition of symptoms and immediate treatment are imperative.

[October 19, 2001 - Letter - FDA]