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U.S. Department of Health and Human Services

Safety

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Videx (didanosine) and Zerit (stavudine) Jan 2001

Fatal lactic acidosis has recently been reported in pregnant women treated throughout gestation with the combination of stavudine and didanosine. Based on these cases, the combination of Zerit (stavudine) and Videx (didanosine) should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk, such as when there are few remaining treatment options.

[January 5, 2001 - Letter - Bristol-Myers Squibb]