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U.S. Department of Health and Human Services

Safety

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Pepcid (famotidine)

Audience: Healthcare Professionals, particularly those caring for elderly patients in nursing home settings

Healthcare professionals are notified about the need for dosage adjustments for patients with moderate renal insufficiency [creatinine clearance <50ml/minute]. The previous labeling recommended adjustments for severe insufficiency only [creatinine clearance <10ml/minute].

[March 23, 2001 - Summary]