Ontak (denileukin diftitox)
Audience: Hemato-oncological healthcare professionals
[Posted 03/15/2006] Ligand Pharmaceuticals and FDA notified healthcare professionals of changes to the WARNINGS section of the prescribing information for Ontak, indicated for the treatment of patients with persistent or recurrent cutaneous T-cell lymphoma. Loss of visual acuity, usually with loss of color vision, has been reported following administration of Ontak. While recovery was reported in some of the affected patients, most patients reported persistent visual impairment.
[March 03, 2006 – Letter – Ligand]