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U.S. Department of Health and Human Services

Safety

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Ibuprofen and Aspirin Taken Together

Audience: Consumers and healthcare professionals
[Posted 09/08/2006] FDA notified consumers and healthcare professionals that taking Ibuprofen for pain relief and aspirin at the same time may interfere with the benefits of aspirin taken for the heart. Ibuprofen can interfere with the anti-platelet effect of low dose aspirin (81 mg per day), that may render aspirin less effective when used for cardioprotection and stroke prevention. Although it is all right to use Ibuprofen and aspirin together, FDA recommends that consumers contact their healthcare professional for more information on the timing of when to take these two medicines, so that both medicines can be effective.

[September 8, 2006 - Healthcare Professional Sheet - FDA]
[September 8, 2006 - Science Paper - FDA]
[September 8, 2006 - Drug Information Page - FDA]