Potency Standard for vWF
•Product
assayed
–Antihemophilic Factor/von Willebrand
Factor Complex (Human)
•Standard
–WHO 1st IS
for vWF Concentrate (NIBSC 00/514)
•9.4 IU vWF: Ristocetin Cofactor/ampoule
•Formulated from a vWF concentrate product by NIBSC
•Available since Nov 2001 after potency calibration against WHO 4th IS
Factor VIII/vWF Plasma (NIBSC 97/586) in a collaborative study
[Hubbard AR et al, Thromb Haemost 2002]