Fluticasone Propionate Reduces Moderate/Severe Exacerbations in COPD

Treatment Group

Fluticasone

Placebo propionate

(n=139) (n=142)

Number of exacerbations*

Total 111 76

Number of Patients with one or moreexacerbations

Total 51 45

Mild 7 (14%) 17 (38%)‡

Moderate/severe 44 (86%) 27 (60%) ‡

* Each patient may have experienced more than one exacerbation. ‡ pɘ.001.

Paggiaro et al. Lancet. 1998; 351:773-780.