Collection of Exacerbation Data in Paggiaro et al., 1998
Exacerbation history: at least 1/ year (treated by physician or hospital) for previous 3 years
Exacerbation: worsening of COPD symptoms requiring changes to normal treatment
Exacerbation severity:
- Mild: patient self-managed at home
- Moderate: patient treated by a physician
- Severe: patient hospitalized
Multiple exacerbations requiring OCS were allowed
Paggiaro et al. Lancet. 1998; 351:773-780.