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U.S. Department of Health and Human Services

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Antiretroviral drugs used in the treatment of HIV infection

Click on drug brand name for additional information.

Multi-class Combination Products

Brand Name Generic Names Manufacturer Name Approval Date Time to Approval
Atripla efavirenz, emtricitabine and tenofovir disoproxil fumarate Bristol-Myers Squibb and Gilead Sciences 12-July-06 2.5 months

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Brand Name Generic Name(s) Manufacturer Name Approval Date Time to Approval
Combivir lamivudine and zidovudine GlaxoSmithKline 27-Sep-97 3.9 months
Emtriva emtricitabine, FTC Gilead Sciences 02-Jul-03 10 months
Epivir lamivudine, 3TC GlaxoSmithKline 17-Nov-95 4.4 months
Epzicom abacavir and lamivudine GlaxoSmithKline 02-Aug-04 10 months
Hivid zalcitabine, dideoxycytidine, ddC Hoffmann-La Roche 19-Jun-92 7.6 months
Retrovir zidovudine, azidothymidine, AZT, ZDV GlaxoSmithKline 19-Mar-87 3.5 months
Trizivir abacavir, zidovudine, and lamivudine GlaxoSmithKline 14-Nov-00 10.9 months
Truvada tenofovir disoproxil fumarate and emtricitabine Gilead Sciences, Inc. 02-Aug-04 5 months
Videx EC enteric coated didanosine, ddI EC Bristol Myers-Squibb 31-Oct-00 9 months
Videx didanosine, dideoxyinosine, ddI Bristol Myers-Squibb 9-Oct-91 6 months
Viread tenofovir disoproxil fumarate, TDF Gilead 26-Oct-01 5.9 months
Zerit stavudine, d4T Bristol Myers-Squibb 24-Jun-94 5.9 months
Ziagen abacavir sulfate, ABC GlaxoSmithKline 17-Dec-98 5.8 months

Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs)

Brand Name Generic Name Manufacturer Name Approval Date Time to Approval
Intelence etravirine Tibotec Therapeutics 18-Jan-08 6 months
Rescriptor delavirdine, DLV Pfizer 4-Apr-97 8.7 months
Sustiva efavirenz, EFV Bristol Myers-Squibb 17-Sep-98 3.2 months
Viramune nevirapine, NVP Boehringer Ingelheim 21-Jun-96 3.9 months

Protease Inhibitors (PIs)

Brand Name Generic Name(s) Manufacturer Name Approval Date Time to Approval
Agenerase amprenavir, APV GlaxoSmithKline 15-Apr-99 6 months
Aptivus tipranavir, TPV Boehringer Ingelheim 22-Jun-05 6 months
Crixivan indinavir, IDV, Merck 13-Mar-96 1.4 months
Fortovase saquinavir (no longer marketed) Hoffmann-La Roche 7-Nov-97 5.9 months
Invirase saquinavir mesylate, SQV Hoffmann-La Roche 6-Dec-95 3.2 months
Kaletra lopinavir and ritonavir, LPV/RTV Abbott Laboratories 15-Sep-00 3.5 months
Lexiva Fosamprenavir Calcium, FOS-APV GlaxoSmithKline 20-Oct-03 10 months
Norvir ritonavir, RTV Abbott Laboratories 1-Mar-96 2.3 months
Prezista darunavir Tibotec, Inc. 23-Jun-06 6 months
Reyataz atazanavir sulfate, ATV Bristol-Myers Squibb 20-Jun-03 6 months
Viracept nelfinavir mesylate, NFV Agouron Pharmaceuticals 14-Mar-97 2.6 months

Fusion Inhibitors

Brand Name Generic Name Manufacturer Name Approval Date Time to Approval
Fuzeon enfuvirtide, T-20 Hoffmann-La Roche & Trimeris 13-Mar-03 6 months

Entry Inhibitors - CCR5 co-receptor antagonist

Brand Name Generic Names Manufacturer Name Approval Date Time to Approval
Selzentry maraviroc Pfizer 06-August-07 8 months

HIV integrase strand transfer inhibitors

Brand Name Generic Names Manufacturer Name Approval Date Time to Approval
Isentress raltegravir Merck & Co., Inc. 12--Oct-07 6 months