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U.S. Department of Health and Human Services

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Swine Influenza (H1N1) and Adults and Adolescents infectedwith HIV: Considerations for Clinicians

The Centers for Disease Control and Prevention (CDC) has published interim guidance for clinicians regarding management of patients with HIV who have been exposed to, or who have contracted the swine influenza (H1N1 virus).

Any influenza carries potential risks for persons with HIV infection. Adults and adolescents with HIV infection, especially persons with low CD4 cell counts, are at higher risk for viral and bacterial lower respiratory tract infections, and for recurrent pneumonias. Because adults and adolescents infected with HIV experience more severe complications of seasonal influenza, it is reasonable to assume that they are also at higher risk for swine influenza complications.

CDC strongly encourages clinicians to familiarize themselves with the interim guidance, and encourages organizations with web sites to link to this guidance, which can be found at http://www.cdc.gov/swineflu/guidance_HIV.htm.

Richard Klein
Office of Special Health Issues
Food and Drug Administration

Kimberly Struble
Division of Antiviral Drug Products
Food and Drug Administration