Select Committee on GRAS Substances (SCOGS) Opinion: Starch Sodium Octenyl Succinate

The GRAS Substances (SCOGS) Database allows access to opinions and conclusions from 115 SCOGS reports published between 1972-1980 on the safety of over 370 Generally Recognized As Safe (GRAS) food substances. The GRAS ingredient reviews were conducted by the Select Committee in response to a 1969 White House directive by President Richard M. Nixon.

Starch Sodium Octenyl Succinate

  • SCOGS-Report Number: 115*
  • Type Of Conclusion: 3
  • ID Code: 66829-29-6
  • Year: 1979
  • 21 CFR Section: 172.892

SCOGS Opinion:

The nutritional properties of starch sodium succinate, starch sodium octenyl succinate and starch aluminum octenyl succinate are similar to those of unmodified starch as indicated by caloric values and growth rates observed in animal feeding experiments. No adverse effects were noted on growth rate or on hematology in short-term rat feeding experiments. However, these experiments were of less than 90 days duration and no gross or histopathological examinations were made. The evidence available is insufficient to answer questions concerning the possible chronic toxicity of these succinates particularly in view of the lack of information on their consumption levels. The Select Committee considers it desirable to undertake long-term animal feeding studies with these modified starches. Information on consumption levels by the U. S. population is also needed. These modified starches are not currently used in infant foods.

In view of the foregoing, the Select Committee concludes that:

While no evidence in the available information on starch sodium succinate, starch sodium octenyl succinate and starch aluminum octenyl succinate demonstrates a hazard to the public when they are used at levels that are now current and in the manner now practiced, uncertainties exist requiring that additional studies should be conducted.

*Complete reports containing details of the safety studies that formed the basis of the opinions and conclusions and are available from the National Technical Information Service (NTIS), 5285 Port Royal Road, Springfield, VA 22161 (703) 605-6000.

Page Last Updated: 07/13/2015
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