The GRAS Substances (SCOGS) Database allows access to opinions and conclusions from 115 SCOGS reports published between 1972-1980 on the safety of over 370 Generally Recognized As Safe (GRAS) food substances. The GRAS ingredient reviews were conducted by the Select Committee in response to a 1969 White House directive by President Richard M. Nixon.
- SCOGS-Report Number: 31*
- Type Of Conclusion: 1
- ID Code: 7772-99-8
- Year: 1974
- 21 CFR Section: 184.1845
Feeding tests of stannous chloride on several species of animals, including observations on carcinogenicty and teratogenicity, at dosage levels significantly above those present in the daily diet, did not reveal evidence that this compound is harmful. Human experience gained after the accidental ingestion of large amounts of tin containing materials or experimental intravenous injection of such materials reinforces this conclusion.
In the light of the foregoing, the Select committee concludes that:
There is no evidence in the available information on stannous chloride that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when it is used at levels that are now current or that might reasonably be expected in future.
*Complete reports containing details of the safety studies that formed the basis of the opinions and conclusions and are available from the National Technical Information Service (NTIS), 5285 Port Royal Road, Springfield, VA 22161 (703) 605-6000.