The GRAS Substances (SCOGS) Database allows access to opinions and conclusions from 115 SCOGS reports published between 1972-1980 on the safety of over 370 Generally Recognized As Safe (GRAS) food substances. The GRAS ingredient reviews were conducted by the Select Committee in response to a 1969 White House directive by President Richard M. Nixon.
Calcium sorbate, potassium sorbate, sodium sorbate, and sorbic acid
|GRAS Substance||ID Code|
21 CFR Section
Sorbic acid and its salts demonstrate very low acute or chronic toxicity for experimental animals. In animals sorbate is metabolized by the normal fatty acid pathway. Although no metabolic or toxicological studies have been conducted in man, the similarity on the pathway of fatty acid metabolism in man and animals suggests that no deleterious effects are to be expected from sorbic acid in the diet even in amounts many times greater than those at which it appears to be used.
Based on these considerations the Select Committee concludes that:
There is no evidence in the available information on sorbic acid and its sodium, potassium and calcium salts that demonstrates, or suggests reasonable grounds to suspect, a hazard to the public when they are used at levels that are now current or that might reasonably be expected in the future.
*Complete reports containing details of the safety studies that formed the basis of the opinions and conclusions and are available from the National Technical Information Service (NTIS), 5285 Port Royal Road, Springfield, VA 22161 (703) 605-6000.