The GRAS Substances (SCOGS) Database allows access to opinions and conclusions from 115 SCOGS reports published between 1972-1980 on the safety of over 370 Generally Recognized As Safe (GRAS) food substances. The GRAS ingredient reviews were conducted by the Select Committee in response to a 1969 White House directive by President Richard M. Nixon.
- SCOGS-Report Number: 13*
- Type Of Conclusion: 2
- ID Code: 9000-30-0
- Year: 1973
- 21 CFR Section: 184.1339
The available information reveals that there are no adverse short-term toxicological consequences in animals of consuming guar gum in amounts exceeding those currently consumed in the normal diet of the U.S. population. In addition, there is no evidence that consumption of guar gum by man has had adverse effects in India or Pakistan, where it has long been used as food, or in the U.S., where it has been used in foods since 1949. However, it should be noted that no long-term animal feeding studies of guar gum have been reported. While the available information does not suggest long-term toxicity, it may be advisable in due course to conduct adequate feeding studies in several species, including pregnant animals, at dosage levels that approximate and exceed the current estimated maximum daily human intakes.
Guar gum, fed at relatively high levels, is reported to be toxic to pregnant mice. Because these toxic levels reported are well in excess of the highest levels now consumed by man, the Select Committee is of the opinion that there are no adverse health aspects of consuming guar gum at current levels. However, it is not possible to determine, without additional data, whether a significant increase in consumption would constitute a dietary hazard.
The Select Committee has weighed the foregoing and concludes that:
There is no evidence in the available information on guar gum that demonstrates a hazard to the public when it is used at levels that are now current and in the manner now practiced.
*Complete reports containing details of the safety studies that formed the basis of the opinions and conclusions and are available from the National Technical Information Service (NTIS), 5285 Port Royal Road, Springfield, VA 22161 (703) 605-6000.