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U.S. Department of Health and Human Services

Emergency Preparedness and Response

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Public Workshop on Burkholderia

 


 

 
 Burkholderia Workshop Information
 

November 29-30, 2012

FDA White Oak Headquarters
10903 New Hampshire Ave
Silver Spring, MD, 20993
 
Day one: 8 a.m. - 5 p.m.  EST
Day two: 8 a.m. - 12 p.m. EST

 
 

On Nov. 29-30, 2012, FDA’s Medical Countermeasures initiative (MCMi) is sponsoring a Public Workshop on Burkholderia (see also Federal Register notice) in collaboration with the:

  • Defense Threat Reduction Agency;
  • National Institutes of Health;
  • Centers for Disease Control and Prevention;
  • U.S. Army Medical Research Institute of Infectious Diseases;
  • Biomedical Advanced Research and Development Authority;
  • Chemical Biological Medical Systems Joint Project Management Office;
  • U.S. Strategic Command Center for Combating Weapons of Mass Destruction; and
  • Joint Science and Technology Office for Chemical and Biological Defense.

The workshop will present the latest information on melioidosis (caused by Burkholderia pseudomallei) and glanders (caused by Burkholderia mallei), building on previous meetings and identifying areas of research needed to advance animal model development and candidate medical countermeasures (MCMs) for approval, licensure, or clearance.

Suggested preparatory reading material for the workshop:
 
1.  Wiersinga WJ, Currie BJ, Peacock SJ; Melioidosis.  N Engl J Med. 2012 Sep 13; 367(11): 1035-1044.
 
2.  Estes DM, Dow SW, Schweizer HP, Torres AG; Present and future therapeutic strategies for melioidosis
     and glanders.  Expert Rev Anti Infect Ther. 2010 Mar; 8(3): 325-38
 
3.  Price EP et al.  Development and validation of Burkholderia pseudomallei-specific real-time PCR assays
     for clinical, environmental or forensic detection applications.  PLoS One. 2012; 7(5): e37723.
     Epub 2012 May 18
 
4.  Soffler C et al.  Development and characterization of a caprine aerosol infection model of
     melioidosis. PLoS One. 2012; 7(8): e43207.  Epub 2012 Aug 15
 
5.  Sim SH et al.  The core and accessory genomes of Burkholderia pseudomallei: implications for
     human melioidosis.  PLoS Pathog. 2008 Oct; 4(10): e1000178. Epub 2008 Oct 17
 
6.  Peacock SJ et al.  Melioidosis vaccines: a systematic review and appraisal of the potential to
     exploit biodefense vaccines for public health purposes. 
     PLoS Negl Trop Dis. 2012 Jan; 6(1): e1488. Epub 2012 Jan 31
 
 

 

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