Drugs
Dispensing Pharmacists and Health Care Provider Instructions
Instructions to identify the wrong fill volume in Carpuject pre-filled cartridges from Hospira, Inc.
This alert applies to Carpuject pre-filled cartridges manufactured by Hospira, Inc. for the following products:
Product Name | Strength | Presentation |
|---|---|---|
Demerol (meperidine HCl) Injection, USP | 25 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 50 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 75 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
Diazepam Injection, USP | 5 mg/mL | 2 mL in 2.5 mL Carpuject, Luer Lock |
Fentanyl Citrate Injection, USP | 100 mcg Fentanyl/2 mL | 2 mL in 2.5 mL Carpuject, Luer Lock |
Heparin Lock Flush Solution, USP | 10 USP heparin units/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 100 USP heparin units/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 100 USP heparin units/mL | 3 mL in 5 mL Carpuject, Luer Lock |
| 10 USP heparin units/mL | 5 mL in 5 mL Carpuject, Luer Lock |
| 100 USP heparin units/mL | 5 mL in 5 mL Carpuject, Luer Lock |
Heparin Sodium Injection, USP | 5,000 USP heparin units/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 10,000 USP heparin units/mL | 0.5 mL in 2.5 mL Carpuject, Luer Lock |
HYDROmorphone HCl Injection, USP | 1 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 2 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 4 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
Ketorolac Tromethamine Injection, USP | 30 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
Labetalol Hydrochloride Injection, USP | 20 mg/4 mL (5 mg/mL) | 4 mL in 5 mL Carpuject, Luer Lock |
Lorazepam Injection, USP | 2 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
Metoprolol Tartrate Injection, USP | 1 mg/mL | 5 mL in 5 mL Carpuject, Luer Lock |
Midazolam Injection, USP | 2 mg/2 mL (1 mg/mL), Preservative-Free | 2 mL in 2.5 mL Cartridge, iSecure Version 2 |
| 2 mg/2 mL (1 mg/mL), Preservative-Free | 2 mL in 2.5 mL Carpuject, Luer Lock |
Morphine Sulfate Injection, USP | 4 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 8 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 10 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
| 15 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
Naloxone Hydrochloride Injection, USP | 0.4 mg/mL | 1 mL in 2.5 mL Carpuject, Luer Lock |
Ondansetron Injection, USP | 2 mg/mL | 2 mL in 2.5 mL Cartridge, iSecure Version 2 |
Sodium Chloride Injection, USP | 0.90% | 2 mL in 2.5 mL Carpuject, Luer Lock |
| 0.90% | 3 mL in 5 mL Carpuject, Luer Lock |
| 0.90% | 5 mL in 5 mL Carpuject, Luer Lock |
Dispensing Pharmacists and Health Care Provider Instructions:
When dispensing any of the potentially affected Hospira Carpuject pre-filled cartridges, visually inspect and verify the fill volume of the Carpuject cartridge before dispensing and before placing the cartridge in the holder to administer the product. Ensure that the actual fill volume matches the labeled fill volume by comparing the volume in the cartridge to the graduation markings displayed on the cartridge. For all cartridge sizes, the volume in the prefilled cartridge should be less than the total volume that the Carpuject is capable of holding.
The correct volumes for the cartridges is as follows:
- For any 1.5 mL capacity Carpuject pre-filled cartridge, the correct amount of fill volume based on the product information is 1 mL.
- For any 2.5 mL capacity Carpuject pre-filled cartridge, the correct amount of fill volume based on the product information may be 0.5 mL, 1 mL, or 2 mL.
- For any 5 mL capacity Carpuject pre-filled cartridge, the correct fill volume may be 3 mL, 4 mL, or 5 mL.
Do not dispense or use any Carpuject pre-filled cartridge having the incorrect fill volume.
Pharmacies should return products that appear to have the incorrect fill volume to Hospira. Hospira has provided photographs of the potentially affected products to assist you with correct fill identification.
