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U.S. Department of Health and Human Services

Drugs

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Information About Triptans

Almotriptan (Axert); Eletriptan (Relpax); Frovatriptan (Frova); Naratriptan (Amerge); Rizatriptan (Maxalt); Sumatriptan (Imitrex); Zolmitriptan (Zomig)

A life-threatening condition called serotonin syndrome can happen when medicines used to treat migraine headaches, 5-hydroxytryptamine receptor agonists (triptans) and medicines used to treat depression, selective serotonin reuptake inhibitors (SSRIs) and selective serotonin/norepinephrine reuptake inhibitors (SNRIs),are used together.