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U.S. Department of Health and Human Services

Drugs

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Resources for You

Abuse-Deterrent Opioid Analgesics

FDA is extremely concerned about the inappropriate use of prescription opioids, which is a major public health challenge for our nation. Opioids can be abused in a number of ways. Abuse-deterrent formulations target the known or expected routes of abuse, such as crushing to snort or dissolving to inject. The science of abuse deterrence is relatively new, and both the formulation technologies and the analytical, clinical, and statistical methods for evaluating those technologies are rapidly evolving.