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U.S. Department of Health and Human Services

Drugs

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PPT Slide - indinavir

This slide shows the mean plasma concentration time course of indinavir in 8 healthy volunteers with indinavir alone or after taking indinavir with St. John’s wort.1 After administration of St. John’s wort, a 57% reduction was observed in the indinavir area under the plasma concentration-time curve (AUC), indicative of reduced exposure to indinavir.

 

 

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