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U.S. Department of Health and Human Services

Drugs

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Cytochrome P450 1A2

  • Induced by smoking tobacco
  • Catalyzes primary metabolism of:
    • Theophylline
    • Imipramine
    • Propranolol
    • Clozapine
  • Inhibited by:
    • Many fluoroquinolone antibiotics
    • Fluvoxamine
    • Cimetidine

 

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