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U.S. Department of Health and Human Services

Drugs

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Cytochrome P450 2C9

  • Absent in 1% Caucasians and African-Americans

  • Primary metabolism of:
    • Most NSAIDs (including COX-2)
    • S-warfarin (the active form)
    • Phenytoin
  • Inhibited by:
    • Fluconazole

 

 

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