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U.S. Department of Health and Human Services


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Contribution of Drug Interactions to the Overall Burden of Preventable ADRs

Leape LL et al. JAMA 1995;274(1):35–43
Raschetti R et al. Eur J Clin Pharmacol 1999;54(12):959–963


  • Drug interactions represent 3–5% of preventable in-hospital ADRs
  • Drug interactions are an important contributor to number of ER visits and hospital admissions


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